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Transcriptional Changes Common to Human Cocaine, Cannabis and Phencyclidine Abuse [PDF]
A major goal of drug abuse research is to identify and understand drug-induced changes in brain function that are common to many or all drugs of abuse. As these may underlie drug dependence and addiction, the purpose of the present study was to examine ...
Elin Lehrmann +2 more
exaly +4 more sources
A Fatal Case of Late Stage Lyme Borreliosis and Substance Abuse
A recent study demonstrated a 1,100% (12-fold) increase in substance abuse after acquiring Lyme borreliosis. Lyme borreliosis and substance abuse have never been adequately studied and deserves greater attention.
RC Bransfield, ME Embers, AJ Dwork
doaj +2 more sources
Drug abuse involving dextromethorphan, an antitussive, has been a social problem in various geographic locations since the 1960s. Ironically, high doses of the drug confer neuroprotective activity with central nervous system and behavioral effects ...
Eun-Joo Shin +4 more
doaj +2 more sources
Synthesis and characterization of phencyclidine and his derivatives [PDF]
Phencyclidine (PCP) or 1-phenyl-cyclohexylpiperidine is the best known representative drug from the compound class of arylcyclohexylamines. On an account of pharmacological activities it belongs to the family of drugs known as a dissociative anesthetics.
Ilić Nataša C. +3 more
doaj +2 more sources
Severe tremors induced by tiletamine e-cigarette and alcohol use: a case report [PDF]
Background and objectivesPolydrug use has caused serious harm to public health, especially involving novel psychoactive substances. Tiletamine, an N-methyl-D-aspartate receptor (NMDAR) antagonist commonly used as a veterinary anesthetic, has recently ...
Bojie Zhou +15 more
doaj +2 more sources
Developmental Neurotoxicity of Alcohol and Anesthetic Drugs Is Augmented by Co-Exposure to Caffeine
Anesthetic and anti-epileptic drugs used in pediatric and obstetric medicine and several drugs, including alcohol, that are abused by pregnant women, trigger widespread neuroapoptosis in the developing brain of several animal species, including non-human
Catherine E. Creeley +2 more
doaj +3 more sources
Gas chromatography with mass spectrometry (GC-MS) is a common analytical technique used for identifying and quantifying drugs of abuse, as well as their metabolites, extracted from biological samples. Depending on the properties of the analyzed compounds,
Ivan Kojić +7 more
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Intracranial Hemorrhage Associated With Phencyclidine Abuse
PHENCYCLIDINE (PCP) is a popular "recreational" drug. Complications of its abuse are myriad and range from mild behavioral disturbances to death. 1-5 Death caused by PCP intoxication is usually due to the "behavioral toxicity" of the drug. 1,2 A case of massive intracranial hemorrhage in a PCP-intoxicated patient is reported herein.
Howard A. Bessen
openaire +3 more sources
Phencyclidine abuse and depression
G, Caracci, P, Migone, S, Mukherjee
openaire +3 more sources
Comeback of ketamine: resurfacing facts and dispelling myths [PDF]
Initially known as CI-581, ketamine was first synthesized in 1962 as a replacement from phencyclidine. It has since been used as an anesthetic and analgesic.
Abhijit Kumar, Amit Kohli
doaj +1 more source

