Results 41 to 50 of about 10,659 (198)

Ocular sequelae from the illicit use of class A drugs [PDF]

, 2004
Aim: To highlight the changes that may take place in the visual system of the class A drug abuser. Methods: A literature review was carried out of ocular/visual sequelae of the more common class A drugs.
Firth, A.Y.
core  

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

British Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander, Dasha Anderson, Luke Baxter, Matthew Claydon, James Rucker, Emma S. J. Robinson   +5 more
wiley   +1 more source

Differential effects of ketamine enantiomers on EEG parameters including the gamma‐delta shift phenomenon

British Journal of Pharmacology, EarlyView.
Background and Purpose Ketamine consists of two enantiomers, (R)‐ketamine and (S)‐ketamine, which exhibit distinct pharmacological properties. Currently, only the (S)‐enantiomer has been approved for the treatment of major depressive disorder, whereas recent clinical studies have failed to demonstrate an antidepressant effect for (R)‐ketamine.
Szabolcs Koncz, Dóra Pothorszki, Noémi Papp, Donát Pál, György Bagdy   +4 more
wiley   +1 more source

Psychoactive substance abuse amongst an urban secondary school population in Enugu, Nigeria: Prevalence and pattern of use

International Journal of Medicine and Health Development, 1999
A survey of psychoactive substance abuse based on a random sample of 181 students was carried out using a self-report drug use questionnaire in April 1998. A general life time prevalence of 85.1% was found. However, most were occasional users.
K O B. Okonkwo, P O Ezeani, U H Ihezue, D F E. Nwagbo   +3 more
doaj  

Primary Care Utilization Among Legally Adjudicated Elder Mistreatment Cases in Comparison to Other Older Adults

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Elder mistreatment is associated with adverse health outcomes and increased Emergency Department (ED) and hospital utilization patterns in the period surrounding initial mistreatment identification. Less is known about outpatient primary care utilization, but it has been hypothesized that elder mistreatment victims may use this care
Jiani Yu, Hao Zhang, Yiyuan Wu, Katherine Wen, Stephenson Strobel, Alyssa Elman, Philip Jeng, Daniel Baek, Yiye Zhang, Zach Gassoumis, Yuhua Bao, Karl Pillemer, Tony Rosen   +12 more
wiley   +1 more source

WORKPLACE SUBSTANCE USE, THE RISK OF OCCUPATIONAL INJURY, AND TESTING [PDF]

, 2005
Over the past 20 years, the "workplace substance abuse prevention industry" has grown enormously in size and has become more sophisticated in its marketing approach. Drug testing alone has become a $6 billion industry.
Zimbardi, Guy
core  

Primary Care Practitioners' Approaches to Deprescribing Opioids for Older Adults With Chronic Pain: A Qualitative Analysis

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Risks related to long‐term opioid therapy for chronic pain are high and may increase over time with aging. Deprescribing may be a beneficial intervention for older adults prescribed chronic opioids. Methods Semi‐structured interviews with hypothetical clinical cases of older adults prescribed opioids for chronic pain: (1) low‐risk ...
Brianna X. Wang, Julia H. Lindenberg, Shoshana J. Herzig, Mara A. Schonberg, Timothy S. Anderson   +4 more
wiley   +1 more source

Marginal bone loss around implants – What does it mean?

Periodontology 2000, EarlyView.
Abstract Background Changes in peri‐implant marginal bone levels (MBL) constitute a central outcome in studies on implant therapy and reflect the integrity of the supporting tissues over time. Aim To summarize current evidence on MBL changes around dental implants, with emphasis on temporal patterns, methods of assessment and their clinical ...
Carlotta Dionigi, Kostas Bougas, Tord Berglundh, Jan Derks   +3 more
wiley   +1 more source

The effects of zinc sulfate on ethyl glucuronide immunoassay urine testing [PDF]

, 2016
Published research in the Journal of Analytical Toxicology and the American Society for Clinical Pathology has confirmed that the presence of Zinc Sulfate in adulterated urine samples can influence the testing results using EMIT and ELISA immunoassay ...
Cawley, Shanna Marie
core   +1 more source

Exercise during 14 days of head down tilt bedrest attenuates motor unit impairments in older humans

Experimental Physiology, EarlyView.
Abstract Head‐down tilt bedrest (HDBR) models the effects of mechanical unloading on neuromuscular function. The efficacy of exercise in preserving motor unit (MU) function in older adults during HDBR remains unclear. This study investigated the effects of 14‐day HDBR on MU properties in older adults and the protective role of exercise.
Philippe St‐Martin, Jean‐Christophe Lagacé, Mathil Ruel, Ahmed Ghachem, Guillaume Léonard, Eleonor Riesco, Mathew Piasecki, Jamie S. McPhee, Isabelle J. Dionne   +8 more
wiley   +1 more source