Results 41 to 50 of about 5,571 (181)
Preclinical models for evaluating psychedelics in the treatment of major depressive disorder
British Journal of Pharmacology, Volume 183, Issue 14, Page 3970-3991, July 2026.Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander +5 more
wiley +1 more source
Drug and Alcohol Review, Volume 45, Issue 5, July 2026.ABSTRACT Introduction We have been funded to examine post‐incarceration health and social outcomes for all people incarcerated in New South Wales, Australia, 2000–2022; assess treatment and services for drug dependence and serious mental illness; and project the impact of expanding intervention coverage. We will use a linked cohort, the Prison Outcomes
Louisa Degenhardt +19 more
wiley +1 more source
Hierarchical clustering identified three main groups of drug abuse cases.
, 2013 Hierarchical clustering of individual transcriptional profiles from comparisons of drug abuse cases and their individual four best-matched controls identified three main groups of drug abusers: Group I (DA1–18), Group II (DA19–34) and Group III (DA35–42).
Kevin G. Becker (48792) +8 more
core +1 more source
Drug Use and Social Connectivity Related to Hepatitis C Infection Among Rural People Who Use Drugs
Journal of Viral Hepatitis, Volume 33, Issue 7, July 2026.ABSTRACT People who use drugs (PWUD) have a disproportionately elevated risk of hepatitis C virus (HCV). Appropriate screening and treatment may be limited, especially in rural environments experiencing healthcare shortages. In order to develop targeted intervention strategies for rural PWUD, we investigated individual and network‐level correlates of ...
Alex Rains +6 more
wiley +1 more source
In Vitro and In Vivo Sequestration of Phencyclidine by Me4Cucurbit[8]uril
, 2020 This work describes the in vitro binding of CB[8] and Me4CB[8] toward a panel of 10 drugs of abuse, and in vitro and in vivo assays to demonstrate the biocompatibility of Me4CB[8].
Steven, Murkli +6 more
core +1 more source
Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba +11 more
wiley +1 more source
In vitro phencyclidine-induced inhibition of lymphocyte proliferation: prevention by cell activation
, 1993 The proliferative response of phytohemagglutinin (PHA)- and interleukin 2 (IL-2)-activated murine splenocytes was studied in the presence of phencyclidine (PCP), a potent psychotomimetic drug of abuse.
P. Di Francesco +16 more
core +1 more source
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Advanced Healthcare Materials, Volume 15, Issue 23, 19 June 2026.Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
Drug Testing and Analysis, Volume 18, Issue 6, Page 771-776, June 2026.Permanent chemical hair straightening was associated with analyte‐dependent changes in hair concentrations, showing increased endogenous GHB levels and decreased alprazolam concentrations after treatment. These results suggest that chemical hair straightening procedures may influence hair concentrations and should be considered when interpreting hair ...
Miriam Blanco‐Ces +5 more
wiley +1 more source
British Journal of Pharmacology, Volume 183, Issue 12, Page 3340-3354, June 2026.Background and Purpose Ketamine consists of two enantiomers, (R)‐ketamine and (S)‐ketamine, which exhibit distinct pharmacological properties. Currently, only the (S)‐enantiomer has been approved for the treatment of major depressive disorder, whereas recent clinical studies have failed to demonstrate an antidepressant effect for (R)‐ketamine.
Szabolcs Koncz +4 more
wiley +1 more source