A potential tumor suppressor role of PLK2 in glioblastoma
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia+5 more
wiley +1 more source
Investigating Viral Causes of Abortions: A Comprehensive Molecular and Pathological Study on Small Ruminants in East Azerbaijan Province, Iran. [PDF]
Khordadmehr M+7 more
europepmc +1 more source
DETECTION OF EPIDERMAL GROWTH-FACTOR RECEPTOR AND C-ERBB-2 GENE AMPLIFICATION IN TRANSITIONAL-CELL BLADDER-CARCINOMA USING THE DIFFERENTIAL PCR TECHNIQUE [PDF]
Vassilis G. Gorgoulis+3 more
openalex +1 more source
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang+7 more
wiley +1 more source
Specific detection of genetically modified potatoes containing <i>asparagine synthetase-1</i> and <i>polyphenol oxidase 5</i> genes derived from potato. [PDF]
Park S, Lee S, Sohn SI, Park T, Shin K.
europepmc +1 more source
Monitoring of early events of experimental woodchuck hepatitis infection: Studies of peripheral blood mononuclear cells by cytofluorometry and PCR [PDF]
Isabelle Chemin
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Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding
The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla+4 more
wiley +1 more source
NS1 Rapid Card Test for Dengue Detection: Insights from the 2023 Outbreak in Bangladesh. [PDF]
Raihan R+12 more
europepmc +1 more source
Maximizing sensitivity and specificity of PCR by preamplification heating
Richard T. D’Aquila+5 more
openalex +2 more sources
PCR amplification from paraffin-embedded tissues: recommendations on fixatives for long-term storage and prospective studies. [PDF]
Catherine E. Greer+2 more
openalex +1 more source