Results 201 to 210 of about 3,963,364 (363)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Technical implementation for african pharmacogenetic studies on <i>CYP2D6</i> from archived breast cancer formalin fixed paraffin-embedded (FFPE) tissues. [PDF]

MethodsX
Nthontho KC, Tawe L, Mugo N, Mabaka R, Contino G, Ndlovu AK, Morse DP, Paganotti GM.   +7 more
europepmc   +1 more source

Specific detection of a basidiomycete, Phlebia brevispora associated with butt rot of Chamaecyparis obtusa, by PCR-based analysis [PDF]

, 2005
Hiroto Suhara, Nitaro Maekawa, Takashi Kubayashi, Ryuichiro Kondo   +3 more
openalex   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

COVID-19 testing and mental health service utilization in Ontario: a population-based cohort study. [PDF]

Int J Public Health
Saqib K, Goel V, Dubin JA, VanderDoes J, Butt ZA.   +4 more
europepmc   +1 more source

Development of Reverse Transcriptase PCR and Nested PCR to Detect Porcine Hemagglutinating Encephalomyelitis Virus

, 2004
Yoshiko Sekiguchi, Junsuke Shirai, Takahide Taniguchi, Eiichi Honda   +3 more
openalex   +2 more sources

LightCycler PCR Assay for Genotyping Codon 634 Mutations in the RET Protooncogene [PDF]

, 2001
María de la Fuente, Celsa Quinteiro, Fernando Domı́nguez, Lourdes Loidi   +3 more
openalex   +1 more source

PCR实验和凝胶电泳实验操作基础

, 2023
昕劢 吴
openalex   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Use of universal reporter primers in multiplex PCR of autosomal loci [PDF]

, 2011
Elaine Cristina Favaro, Denilce R. Sumita, M.R. Whittle   +2 more
openalex   +1 more source