Results 221 to 230 of about 3,963,364 (363)

A high-throughput, streamlined cloning protocol to generate guide RNAs for CRISPR activation. [PDF]

Front Genome Ed
Zhu S, Tamez González AA, Alokda A, Van Raamsdonk JM.   +3 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Diagnostic Accuracy of a Simple and Rapid Diagnostic Test RLDT for the Detection of Cholera in Bangladesh. [PDF]

Open Forum Infect Dis
Islam K, Khan AI, Bhuiyan MDTR, He F, Khan ZH, Islam MT, Qadri F, Chakraborty S.   +7 more
europepmc   +1 more source

The Association between Diabetes Mellitus Type 1 and Epstein-Barr virus Infection at Serological and PCR levels [PDF]

Nehal M. Harfoush, W. Zaghloul, Wafaa Mowafy, Nanees Salem, Raghdaa Shrief   +4 more
openalex   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Evaluation and comparison of three qPCR commercial assays and three automated platforms for the detection of monkeypox virus DNA. [PDF]

Microbiol Spectr
Usal M, Andréani J, Truffot A, Chevalier C, Larrat S, Lupo J, Morand P, Ferraris O, Germi R.   +8 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Evidence Gaps and Global Patterns in Leishmaniasis Control: A Scoping Review of Clinical, Diagnostic, and Treatment Strategies. [PDF]

J Parasitol Res
Mohammed MW, Aboagye YO, Anyanful A, Kyei S, Asare KK.   +4 more
europepmc   +1 more source

Detection of respiratory herpesviruses in foals and adult horses determined by nested multiplex PCR

, 2006
L. Wang, Sharanne Raidal, A. Pizzirani, G.E. Wilcox   +3 more
openalex   +2 more sources

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source