Results 101 to 110 of about 173,457,123 (221)

Plasmodium falciparum Parasites With Histidine‐Rich Protein 2 (pfhrp2) and pfhrp3 Gene Deletions in Frontier Endemic Regions of Brazilian Amazon

Tropical Medicine &International Health, EarlyView.
ABSTRACT Studies reporting deletions of the pfhrp2 and pfhrp3 genes in P. falciparum populations in various malaria‐endemic countries, including countries bordering Brazil, are increasing. Individuals infected with P. falciparum carrying deletions of the pfhrp2/3 genes may yield false‐negative results in Rapid Diagnostic Tests (RDTs) based on the ...
Jéssica de Oliveira Bonsanto Gonçalves, Simone da Silva Santos, Rodrigo Medeiros Martorano, Jaime Louzada, Victoria Martins Roque Almeida, Lucas Rego Viana, Josely Oliveira Ferreira, Anielle Pina Costa, André Siqueira, Martha Cecília Suárez‐Mutis   +9 more
wiley   +1 more source

Detection of malaria parasites by nested PCR in south-eastern, Iran: Evidence of highly mixed infections in Chahbahar district

Malaria Journal, 2002
Background Rapid diagnosis and correct treatment of cases are the main objectives of control programs in malaria-endemic areas. Methods and results To evaluate these criteria and in a comparative study, blood specimens were collected from 120 volunteers ...
Zare Ahmad, Najafabadi Sohaila, Zakeri Sedigheh, Djadid Navid   +3 more
doaj   +1 more source

Donor management implications for high‐sensitivity detection of low‐level malaria parasitemia in blood donor screening

Transfusion, EarlyView.
Abstract Introduction Transfusion‐transmitted malaria can occur when donors have unrecognized asymptomatic infection with submicroscopic parasitemia, highlighting the need to detect low‐level parasitemia in blood donor screening. However, these highly sensitive blood donor testing algorithms may refer donors to clinicians who use diagnostic algorithms ...
Carmen L. Charlton, Valerie Conrod, Dilini Kumaran, Craig Jenkins, Sandy Shokoples, LeeAnn Turnbull, Ruwandi Kariyawasam, Chantale Pambrun, Steven J. Drews   +8 more
wiley   +1 more source

Overuse of artemisinin-combination therapy in Mto wa Mbu (river of mosquitoes), an area misinterpreted as high endemic for malaria. [PDF]

, 2008
BACKGROUND: Adequate malaria diagnosis and treatment remain major difficulties in rural sub-Saharan Africa. These issues deserve renewed attention in the light of first-line treatment with expensive artemisinin-combination therapy (ACT) and changing ...
Bianca Mengerink, Mosha, F., Bousema, Teun, Arnold Ndaro, Shekalaghe Seif, Shekalaghe, Seif, Sauerwein Robert, Sauerwein, R.W., Gosling Roly, Seif Shekalaghe, Shekalaghe, S., Megiroo, Simon, Mwanziva Charles, Ndaro, A., Frank Mosha, Drakeley, Chris, Gosling, R., Mengerink, Bianca, Chris Drakeley, Teun Bousema, Mengerink, B., Robert Sauerwein, Megiroo Simon, Bousema, T., Mosha, Frank, Drakeley Chris, Mwanziva, C., Mengerink Bianca, Mwanziva, Charles, Megiroo, S., Bousema Teun, Ndaro Arnold, Gosling, Roly, Drakeley, C., Charles Mwanziva, Sauerwein, Robert, Mosha Frank, Simon Megiroo, Roly Gosling, Ndaro, Arnold   +39 more
core   +1 more source

A molecular survey of febrile cases in malaria-endemic areas along China-Myanmar border in Yunnan province, People’s Republic of China

Parasite, 2014
Background: Imported malaria is a major threat to neighboring malaria-eliminating countries such as P.R. China and is difficult to monitor. A molecular survey of febrile patients with a history of traveling abroad along the Myanmar-China endemic border ...
Zhou Xia, Huang Ji-Lei, Njuabe Metoh Theresia, Li Sheng-Guo, Chen Jun-Hu, Zhou Xiao-Nong   +5 more
doaj   +1 more source

Molecular characterization of CD36 deficiency in blood donors of Middle Eastern and African origin reveals transcript‐level defects beyond genomic variants

Transfusion, EarlyView.
Abstract Background The increasing diversity of blood donor populations has created new challenges for transfusion services worldwide. The identification of donors lacking relevant high‐prevalence antigens is becoming increasingly important to ensure compatible blood products for alloimmunized patients and to support the development of rare donor ...
Sarah Petermann, Inga Stellmacher, Brigitte K. Flesch, Tanja Rehling, Irina Häcker, Marc F. Schetelig, Alexander Carbol, Lambros Kordelas   +7 more
wiley   +1 more source

Use of Nested PCR for Differential Diagnosis of Falciparum Malaria Reinfection and Relapse in Drug-Resistant Patients

Bulletin of Experimental Biology and Medicine, 2002
Microscopic examination does not allow differentiation of drug-resistant P. falciparum infection relapse from reinfection. However, this differential diagnosis is essential for adequate therapy. Three highly polymorphic P. falciparum genes (msp1, msp2, and glurp) and their alleles reflecting the structural state of these genes were used as genetic ...
Dao L.D., Rabinovich S.A., Van Ha N.
openaire   +4 more sources

Disparities of Plasmodium falciparum infection, malaria-related morbidity and access to malaria prevention and treatment among school-aged children : a national cross-sectional survey in Côte d'Ivoire [PDF]

, 2015
There is limited knowledge on the malaria burden of school-aged children in Côte d'Ivoire. The aim of this study was to assess Plasmodium falciparum infection, malaria-related morbidity, use of preventive measures and treatment against malaria, and ...
Silué, Kigbafori D., Eveline Hürlimann, N'Dri, Prisca B., Assi, Serge-Brice, Utzinger, Jürg, Yapi, Richard B., Cinthia A Acka, Penelope Vounatsou, Clarisse A Houngbedji, Richard B Yapi, Benjamin G Koudou, Fantodji, Agathe, Jürg Utzinger, Acka, Cinthia A., Houngbedji, Clarisse A., Giovanna Raso, Raso, Giovanna, Gotianwa Soro, Koudou, Benjamin G., Prisca B N’Dri, Serge-Brice Assi, Soro, Gotianwa, N'Goran, Eliézer K., Hürlimann, Eveline, Kigbafori D Silué, Eliézer K N’Goran, Vounatsou, Penelope, Agathe Fantodji, Utzinger J, N'Goran EK, Koudou BG, Soro G, Acka CA, Houngbedji CA, Yapi RB, Fantodji A, Raso G, Vounatsou P, Assi SB, Silué KD, Hürlimann E, N'Dri PB   +41 more
core   +1 more source

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

American Journal of Medical Genetics Part A, Volume 200, Issue 12, Page 2719-2737, December 2026.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun, Zhifeng Zhu, Fengye Zhou, Ying Liu, Chunfang Liang, Haitao Ju, Lin Lu, Zhaoli Yan   +7 more
wiley   +1 more source

Willingness to use a rapid diagnostic test for malaria in a rural area of central Côte d'Ivoire [PDF]

, 2012
: BACKGROUND: Malaria mortality is mainly a direct consequence of inadequate and/or delayed diagnosis and case management. Some important control interventions (e.g.
Koudou, Benjamin, Raso, Giovanna, Tanner, M., Utzinger, Jürg, Ouattara Allassane F, Utzinger, J., Ouattara, Allassane F, Comoé, C. C., Raso, G., Tanner Marcel, Utzinger Jürg, Comoé Colombe Coffie, Koudou, B. G., Ouattara, A. F., Raso Giovanna, Koudou Benjamin G, Comoé, Colombe Coffie, Tanner, Marcel, Colombe Coffie Comoé, Utzinger J, Marcel Tanner, Benjamin G Koudou, Koudou BG, Jürg Utzinger, Giovanna Raso, Allassane F Ouattara, Raso G, Comoé CC, Ouattara AF, Tanner M   +29 more
core   +2 more sources