Transmission of Porcine Circovirus 3 (PCV3) by Xenotransplantation of Pig Hearts into Baboons [PDF]
Porcine circovirus 3 (PCV3) is a newly described member of the virus family Circoviridae. PCV3 is highly distributed among pigs and wild boars worldwide.
Barbara Kessler +2 more
exaly +6 more sources
Histological Lesions and Replication Sites of PCV3 in Naturally Infected Pigs [PDF]
Porcine circovirus type 3 (PCV3) has been recently described as a potential cause of abortions and systemic vasculitis in pigs. Although the virus has been detected by real-time PCR in several porcine tissues from countries worldwide, PCV3-associated ...
Albert Rovira +2 more
exaly +5 more sources
Construction and immunogenicity evaluation of a bivalent nanoparticle based on mi3 displaying porcine circovirus type 2 and type 3 capsid proteins [PDF]
Porcine circovirus type 2 (PCV2) and type 3 (PCV3) pose severe threats to swine health worldwide. PCV2 field strains continuously mutate with the co-circulation of multiple genotypes, resulting in potential immune escape from existing vaccines.
Baishi Lei +15 more
doaj +2 more sources
Four genotypes of circovirus have been recognized in swine, with PCV2 and PCV3 being the most associated with clinical manifestations, while PCV4 does not have a defined disease.
Jairo Jaime, Diana S Vargas-Bermudez
exaly +3 more sources
Molecular Surveillance and Evolutionary Dynamics of Porcine Circovirus Types 2 and 3 in China, 2022-2025. [PDF]
Porcine circovirus types 2 (PCV2) and 3 (PCV3) are globally distributed pathogens associated with reproductive disorders, subclinical infections, and multifactorial disease complexes in swine. To elucidate their epidemiological and evolutionary patterns in China, we examined 8426 clinical samples collected from 28 provincial‐level regions between 2022 ...
Chen Y +11 more
europepmc +2 more sources
Emerging Challenges and Advances in Porcine Circovirus: A Decade in Review. [PDF]
Over the past decade, porcine circoviruses (PCVs) have continued to pose a significant threat to global swine health, and pivotal discoveries have significantly reshaped our understanding of their biology and control. Extensive genomic surveillance has expanded porcine circovirus 2 (PCV2) genotyping from four to at least eight lineages, with PCV2d now ...
Zheng J, Zhang G, Li P, Ren L.
europepmc +2 more sources
Structural basis and immunogenic efficacy of porcine circovirus type 3 virus-like particle [PDF]
Porcine circovirus type 3 (PCV3) is an emerging swine pathogen associated with reproductive failure and systemic inflammation, but vaccines for related PCV2 provide limited cross-protection.
Jinfu Su +15 more
doaj +2 more sources
Emergence of a Novel CRESS-DNA Virus Associated with Swine Reproductive Failure in China. [PDF]
The continuous emergence of circular Rep‐encoding single‐stranded (CRESS) DNA viruses across diverse hosts has been closely associated with the occurrence of severe diseases. Four circoviruses within the genus Circovirus have been identified in pigs, including porcine circovirus Type 1 (PCV1), PCV2, PCV3, PCV4, and PCV5.
Liu X +12 more
europepmc +2 more sources
DEAD-box RNA helicase 10 inhibits porcine circovirus type 3 replication by interacting with the viral capsid protein and activating interferon responses [PDF]
Porcine circovirus type 3 (PCV3) is an emerging pathogen that causes porcine dermatitis and nephropathy syndrome-like symptoms, multisystemic inflammation, and reproductive failure.
Jianwei Zhou +12 more
doaj +2 more sources
Animal Welfare-Friendly Noninvasive Oral Fluid in Swine Diagnostics: Current Applications in Disease Monitoring, Key Challenges and Future Directions. [PDF]
The integration of oral fluid (OF) sampling into veterinary diagnostics represents a significant shift in animal herd health monitoring, offering a noninvasive alternative to traditional blood‐based methods. OF, predominantly composed of saliva, mucosal transudate and plasma‐derived components, contains immunoglobulins, acute‐phase proteins and nucleic
Chouhan CS +3 more
europepmc +2 more sources

