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Isolation of PCV3 from Perinatal and Reproductive Cases of PCV3-Associated Disease and In Vivo Characterization of PCV3 Replication in CD/CD Growing Pigs [PDF]

open access: yesViruses, 2020
Porcine circovirus 3 (PCV3) has been identified as a putative swine pathogen with a subset of infections resulting in stillborn and mummified fetuses, encephalitis and myocarditis in perinatal, and periarteritis in growing pigs.
Juan Mora-Díaz   +7 more
doaj   +7 more sources

DDX21 Promotes PCV3 Replication by Binding to Cap Protein and Inhibiting Interferon Responses

open access: yesViruses
Porcine circovirus type 3 (PCV3) is an emerging pathogen that causes porcine dermatitis, nephropathy syndrome-like symptoms, multisystemic inflammation, and reproductive failure.
Haoyu Sun   +11 more
doaj   +4 more sources

Recent Progress on Epidemiology and Pathobiology of Porcine Circovirus 3

open access: yesViruses, 2021
The recently discovered porcine circovirus 3 (PCV3) belongs to the Circovirus genus of the Circoviridae family together with the other three PCVs, PCV1, PCV2, and PCV4.
Si Chen   +4 more
doaj   +2 more sources

Full genome characterization of porcine circovirus type 3 isolates reveals the existence of two distinct groups of virus strains

open access: yesVirology Journal, 2018
Background The occurrence of the novel porcine circovirus type 3 (PCV3) was reported from the Americas, Asia and Europe. Although this virus was detected in association with various clinical syndromes in pigs, its role as possible swine pathogen remains ...
Robert Fux   +7 more
doaj   +1 more source

Development and application of a baculovirus-expressed capsid protein-based indirect ELISA for detection of porcine circovirus 3 IgG antibodies

open access: yesBMC Veterinary Research, 2019
Background Porcine circovirus type 3 (PCV3), recently widely isolated from pigs with various clinical conditions, is likely globally epidemic. However, development of serological diagnosis for PCV3 in pigs is ongoing. Our objectives were to: 1) establish
Sujiao Zhang   +9 more
doaj   +1 more source

Detection of Porcine Circovirus Type 3 in Serum, Semen, Oral Fluid, and Preputial Fluid Samples of Boars

open access: yesVeterinary Sciences, 2023
Porcine circovirus type 3 (PCV3) is commonly associated with clinical symptoms such as porcine dermatitis and nephropathy syndrome (PDNS)-like lesions, respiratory signs, and reproductive disorders.
Song Qi   +6 more
doaj   +1 more source

First detection and phylogenetic analysis of porcine circovirus 3 in female donkeys with reproductive disorders

open access: yesBMC Veterinary Research, 2021
Background PCV3 is a pathogen associated with porcine dermatitis and nephropathy syndrome (PDNS)-like clinical signs, reproductive failure, and cardiac and multiorgan inflammation, which was newly identified in 2016 in sows in USA.
Tongtong Wang   +14 more
doaj   +1 more source

Heme Oxygenase-1 and Its Metabolites Carbon Monoxide and Biliverdin, but Not Iron, Exert Antiviral Activity against Porcine Circovirus Type 3

open access: yesMicrobiology Spectrum, 2023
Porcine circovirus type 3 (PCV3) is a newly discovered pathogen that causes porcine dermatitis and nephropathy syndrome (PDNS)-like clinical signs, multisystemic inflammation, and reproductive failure.
Lei Hou   +8 more
doaj   +1 more source

DEAD-box RNA helicase 10 inhibits porcine circovirus type 3 replication by interacting with the viral capsid protein and activating interferon responses

open access: yesJournal of Virology
Porcine circovirus type 3 (PCV3) is an emerging pathogen that causes porcine dermatitis and nephropathy syndrome-like symptoms, multisystemic inflammation, and reproductive failure.
Jianwei Zhou   +12 more
doaj   +1 more source

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