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DDX21 Promotes PCV3 Replication by Binding to Cap Protein and Inhibiting Interferon Responses [PDF]

open access: yesViruses
Porcine circovirus type 3 (PCV3) is an emerging pathogen that causes porcine dermatitis, nephropathy syndrome-like symptoms, multisystemic inflammation, and reproductive failure.
Haoyu Sun   +11 more
doaj   +5 more sources

Evaluation of IgM, IgA, and IgG Antibody Responses Against PCV3 and PCV2 in Tissues of Aborted Fetuses from Late-Term Co-Infected Sows [PDF]

open access: yesPathogens
Porcine circovirus type 2 (PCV2) is a ubiquitous pathogen, and co-infections with the emerging PCV3 are increasingly reported. Both PCV2 and PCV3 have been implicated in reproductive failure, yet the diagnostic criteria for PCV3 remain under development.
Alexandra Henao-Díaz   +1 more
exaly   +5 more sources

Transmission of Porcine Circovirus 3 (PCV3) by Xenotransplantation of Pig Hearts into Baboons [PDF]

open access: yesViruses, 2019
Porcine circovirus 3 (PCV3) is a newly described member of the virus family Circoviridae. PCV3 is highly distributed among pigs and wild boars worldwide.
Barbara Kessler   +2 more
exaly   +6 more sources

Detection of PCV3 in various sample types from wild boars in Poland [PDF]

open access: yesBMC Vet Res
In 2016, the new circovirus, PCV3, was discovered in pigs displaying various clinical symptoms. To date, this virus is believed to be pathogenic for pigs and considered equal or greater economic significance for the porcine sector compared to PCV2 ...
E. Czyżewska-Dors   +5 more
semanticscholar   +4 more sources

Histological Lesions and Replication Sites of PCV3 in Naturally Infected Pigs [PDF]

open access: yesAnimals, 2021
Porcine circovirus type 3 (PCV3) has been recently described as a potential cause of abortions and systemic vasculitis in pigs. Although the virus has been detected by real-time PCR in several porcine tissues from countries worldwide, PCV3-associated ...
Albert Rovira   +2 more
exaly   +5 more sources

The Prevalence and Genetic Diversity of PCV3 and PCV2 in Colombia and PCV4 Survey during 2015–2016 and 2018–2019

open access: yesPathogens, 2022
Four genotypes of circovirus have been recognized in swine, with PCV2 and PCV3 being the most associated with clinical manifestations, while PCV4 does not have a defined disease.
Jairo Jaime   +2 more
exaly   +4 more sources

Immunogenicity Analysis of PCV3 Capsid Highly Expressed Using Baculovirus [PDF]

open access: yesInt J Mol Sci
Porcine circovirus type 3 (PCV3) capsid protein (Cap) is a key antigen for immunological studies and vaccine development. Different optimized PCV3 ORF2 sequences were used to construct six baculovirus transfer plasmids, with the pOET1.1-based design ...
Baoge Zhang   +3 more
semanticscholar   +3 more sources

Isolation of PCV3 from Perinatal and Reproductive Cases of PCV3-Associated Disease and In Vivo Characterization of PCV3 Replication in CD/CD Growing Pigs [PDF]

open access: yesViruses, 2020
Porcine circovirus 3 (PCV3) has been identified as a putative swine pathogen with a subset of infections resulting in stillborn and mummified fetuses, encephalitis and myocarditis in perinatal, and periarteritis in growing pigs.
Juan Mora-Díaz   +7 more
doaj   +5 more sources

Detection and Complete Genomic Analysis of Porcine circovirus 3 (PCV3) in Diarrheic Pigs from the Dominican Republic: First Report on PCV3 from the Caribbean Region

open access: yesPathogens, 2023
The increasing detection of Porcine circovirus 3 (PCV3, family Circoviridae) in clinically ill pigs worldwide has raised concerns on the implications of the virus on porcine health and the pork industry.
Kerry Gainor   +5 more
doaj   +4 more sources

Comparative Pathogenicity of PCV2, PCV3, and PCV4 in Piglets: Insights Into Clinical, Pathological, and Immunological Features [PDF]

open access: yesTransbound Emerg Dis
Porcine circoviruses (PCVs) have been a significant concern in swine health, with PCV2 being a well-established pathogen. However, the newly discovered PCV3 and PCV4 have emerged, and their impact on piglets remains less understood.
Jiawei Zheng   +7 more
semanticscholar   +4 more sources

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