Results 11 to 20 of about 3,128,138 (270)

PD-1/PD-L1 inhibitors [PDF]

Current Opinion in Pharmacology, 2015
Tumors may adopt normal physiologic checkpoints for immunomodulation leading to an imbalance between tumor growth and host surveillance. Antibodies targeting the PD-1/PD-L1 checkpoint have shown dynamic and durable tumor regressions, suggesting a rebalancing of the host-tumor interaction.
Joel, Sunshine, Janis M, Taube
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PD-L1 [PDF]

Journal of Clinical Pathology, 2017
Programmed death ligand 1 (PD-L1) is the principal ligand of programmed death 1 (PD-1), a coinhibitory receptor that can be constitutively expressed or induced in myeloid, lymphoid, normal epithelial cells and in cancer. Under physiological conditions, the PD-1/PD-L1 interaction is essential in the development of immune tolerance preventing excessive ...
Kythreotou A., Siddique A., Mauri F. A., Bower M., Pinato D. J.   +4 more
openaire   +4 more sources

Connecting Binuclear Pd(III) and Mononuclear Pd(IV) Chemistry by Pd–Pd Bond Cleavage [PDF]

Journal of the American Chemical Society, 2012
Oxidation of binuclear Pd(II) complexes with PhICl(2) or PhI(OAc)(2) has previously been shown to afford binuclear Pd(III) complexes featuring a Pd-Pd bond. In contrast, oxidation of binuclear Pd(II) complexes with electrophilic trifluoromethylating ("CF(3)(+)") reagents has been reported to afford mononuclear Pd(IV) complexes.
Powers, DC, Lee, E, Ariafard, A, Sanford, MS, Yates, BF, Canty, AJ, Ritter, T   +6 more
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PD-1, PD-L1, PD-L2 expression in the chordoma microenvironment [PDF]

Journal of Neuro-Oncology, 2014
Chordomas are rare malignant tumors that are postulated to arise from remnants of the notochord. Currently, the interaction between chordomas and the host immune system is poorly understood. The checkpoint protein, PD-1 is expressed by circulating lymphocytes and is a marker of activation and exhaustion.
Dimitrios, Mathios, Jacob, Ruzevick, Christopher M, Jackson, Haiying, Xu, Sagar R, Shah, Janis M, Taube, Peter C, Burger, Edward F, McCarthy, Alfredo, Quinones-Hinojosa, Drew M, Pardoll, Michael, Lim   +10 more
openaire   +2 more sources

Fractal-based autonomous partial discharge pattern recognition method for MV motors [PDF]

, 2018
On-line partial discharge (PD) monitoring is being increasingly adopted to improve the asset management and maintenance of medium-voltage (MV) motors. This study presents a novel method for autonomous analysis and classification of motor PD patterns in ...
Cacciari M., Danikas M., Jian L., Keller J.M., Kheirmand A., Kreuger F.F.H., Krivda A., Li S., Mandelbrot B., Salama M., Song X., Stone G., Xiaosheng P., Xiaoxing Z., Xiaoxing Z., Zhou C.   +15 more
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Simultaneous quantifications of four purine derivatives biomarkers in cow milk by SPE HPLC-DAD

Czech Journal of Food Sciences, 2021
In this study, simultaneous quantification of allantoin, uric acid, xanthine, and hypoxanthine in cow milk by solid phase extraction (SPE) and high performance liquid chromatography-diode array detection (HPLC-DAD) method was perform.
Mihaela Vlassa, Filip Miuța, Cătălin Dragomir   +2 more
doaj   +1 more source

Levodopa-carbidopa intestinal gel therapy in Parkinson’s disease: Procedure complications [PDF]

Romanian Journal of Neurology, 2020
Objectives. Continuous delivery of levodopa-carbidopa intestinal gel (LCIG) represents a gold standard option for the treatment of advanced PD and the benefits of intestinal gel delivery are significative superior from those obtained with available ...
Luminita Celia Popa, Daniel-Corneliu Leucuta, Nicoleta Tohanean, Stefan-Lucian Popa, Lacramioara Perju-Dumbrava   +4 more
doaj   +1 more source

Palladium nanoparticles by electrospinning from poly(acrylonitrile-co-acrylic acid)-PdCl2 solutions. Relations between preparation conditions, particle size, and catalytic activity [PDF]

, 2004
Catalytic palladium (Pd) nanoparticles on electrospun copolymers of acrylonitrile and acrylic acid (PAN-AA) mats were produced via reduction of PdCl2 with hydrazine.
Basu B., Bronstein L., Bronstein L. M., Bönnemann H., Demir M. M., Doshi J., Forster J. F., Gui Z., Hedden R. C., Hirai H., Horswell S., Itoh H., Jia H., Ledaux M., Li Y. D., Sidorov S. N., Spatz J. P., Sulman E., Willis M., Wonterghem J., Yang Q. B., Yonezawa T.   +21 more
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Research on parallel nonlinear control system of PD and RBF neural network based on U model

Automatika, 2020
The modelling problem of nonlinear control system is studied, and a higher generality nonlinear U model is established. Based on the nonlinear U model, RBF neural network and PD parallel control algorithm are proposed.
Fengxia Xu, Deqiang Tang, Shanshan Wang
doaj   +1 more source

Investigation of hydrazine electrooxidation performance of carbon nanotube supported Pd monometallic direct hydrazine fuel cell anode catalysts

MANAS: Journal of Engineering, 2020
In this study, carbon nanotube (CNT) supported Pd catalysts at varying Pd molar ratios are prepared via NaBH4 reduction method. Catalysts prepared for hydrazine electrooxidation are characterized via N2 adsorption-desorption measurements (BET), X-ray ...
Hilal Demir Kıvrak, Adnan Aldemir, Ömer Er, Ali Cavak   +3 more
doaj   +1 more source