Results 31 to 40 of about 716,189 (248)
Advanced Biology, 2021 AbstractT cell activation is a fine‐tuned process that involves T cell receptor and costimulation signals. To prevent undue activation of T cells, inhibitory molecules including PD‐1 (programmed death 1) are induced and function as brakes for T cell signaling.
Qi Wang +3 more
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Regulation of PD-1/PD-L1 pathway and resistance to PD-1/PD-L1 blockade
Oncotarget, 2017 Immune checkpoint blockades, such as inhibitors against programmed death 1 (PD-1) and its ligand (PD-L1), have received extensive attention in the past decade because of their dramatic clinical outcomes in advanced malignancies. However, both primary and acquired resistance becomes one of the major obstacles, which greatly limits the long-lasting ...
Bai, Jie +5 more
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CLINICAL ASPECTS OF SLEEP DISORDERS IN PATIENTS WITH PARKINSON’S DISEASE
Клиническая практика, 2017 According to the scientific literature of sleep disturbance in patients with Parkinson’s disease meet from 51 to 85 %. In this study, PD patients with sleep disturbances were found in 50.1% (348 of 694 patients) were included in the registry (it surveyed
O A Andrienko
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Using the Palladium as core and Platinum as shell for ORR [PDF]
Hydrogen, Fuel Cell & Energy Storage, 2014 In this work, electrocatalyst with core-shell structure (Pd as core and Pt as shell on VulcanXC-72R) was synthesis. Not only this structure can reduce the amount of platinum but it also can increase the gas diffusion electrode (GDE) performance in ...
Masoumeh Javaheri
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Early Predictors in the Onset of Type 2 Diabetes at Different Fasting Blood Glucose Levels
Diabetes, Metabolic Syndrome and Obesity, 2021 Xiaomin Xie,* Guirong Bai,* Huili Liu, Li Zhang, YanTing He, Dan Qiang, Xiaoyan Zou Department of Endocrinology, The First People’s Hospital of Yinchuan, Yinchuan, 750001, People’s Republic of China*These authors contributed equally to this ...
Xie X +6 more
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A proposed benchmark model using a modularised approach to calculate IFRS 9 expected credit loss
Cogent Economics & Finance, 2020 The objective of this paper is to develop a methodology to calculate expected credit loss (ECL) using a transparent-modularised approach utilising three components: probability of default (PD), loss given default (LGD) and exposure at default (EAD).
Willem Daniel Schutte +4 more
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PD-L1 and PD-L2 differ in their molecular mechanisms of interaction with PD-1 [PDF]
International Immunology, 2010 The programmed death-1 (PD-1) molecule is involved in peripheral tolerance and in the immune escape mechanisms during chronic viral infections and cancer. PD-1 interacts with two ligands, PD-L1 and PD-L2. We have investigated the molecular mechanisms of PD-1 interactions with its ligands by surface plasmon resonance and cell surface binding as well as ...
Marguerite, Ghiotto +6 more
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استفاده ترکیبی از چند روش در امکان سنجی قابلیت پیاده مداری معابر شهری [PDF]
معماری و شهرسازی ایران, 2019 پیاده مداری اهمیتی اساسی در ادراک هویت فضایی و دریافت کیفیت محیط دارد و به این لحاظ مورد توجه نظریه پردازان متعددی قرار گرفته است. با توجه به تلاش های اخیر برنامه ریزان و طراحان جهت تشویق مردم به پیاده روی، مدل ها و روش های بسیاری جهت امکان سنجی پیاده ...
پویان شهابیان
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A pragmatic macroeconomic default risk adjustment in developing countries
South African Journal of Economic and Management SciencesBackground: The expected credit loss (ECL) framework of International Financial Reporting Standards Foundation (IFRS) 9 typically comprises three components: probability of default (PD), loss given default (LGD) and exposure at default (EAD). Among these,
Suben Moodley +2 more
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SPION-A-Pd(EDTA) (superparamagnetic iron oxide nanoparticles-A-ethylendiamine tetraacetic acid) as a robust nanocatalyst for Buchwald-Hartwig C-N Coupling Reaction [PDF]
Nanochemistry Research, 2017 During thelast20-30 years, palladium-catalyzed reactions have witnessed tremendous advances in the industrial and organic reactions such as hydrogenation, coupling, cyanation and amination.
Marzieh Ghotbinejad +5 more
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