Blocking interaction between SHP2 and PD‐1 denotes a novel opportunity for developing PD‐1 inhibitors [PDF]
, 2020 Small molecular PD‐1 inhibitors are lacking in current immuno‐oncology clinic. PD‐1/PD‐L1 antibody inhibitors currently approved for clinical usage block interaction between PD‐L1 and PD‐1 to enhance cytotoxicity of CD8+ cytotoxic T lymphocyte (CTL ...
Chen, Liang +15 more
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PD-1, PD-L1, PD-L2 expression in the chordoma microenvironment [PDF]
Journal of Neuro-Oncology, 2014 Chordomas are rare malignant tumors that are postulated to arise from remnants of the notochord. Currently, the interaction between chordomas and the host immune system is poorly understood. The checkpoint protein, PD-1 is expressed by circulating lymphocytes and is a marker of activation and exhaustion.
Dimitrios, Mathios +10 more
openaire +2 more sources
Novel nonalloyed thermally stable Pd/Sn and Pd/Sn/Au ohmic contacts for the fabrication of GaAs MESFETs [PDF]
, 2001 GaAs metal-semiconductor field-effect transistors (MESFETs) have been fabricated utilizing thermally stable Pd/Sn and Pd/Sn/Au ohmic contacts for the first time. MESFETs with Pd/Ge ohmic contacts are fabricated for comparison.
Islam, Md. Shafiqul, McNally, Patrick J.
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GSTM1 null polymorphism and palmar dermatoglypics in oral leukoplakia
Indian Journal of Dental Research, 2021 Background: An individual's risk towards development of cancer depends not only on environmental factors or extrinsic exposure to carcinogens but also on individual's genetic susceptibility.
Lakshanika Yogesh, Nalini Aswath
doaj +1 more source
Bis[μ-bis(diphenylphosphino)methane-К²P:P’]bis[(saccharinato-КN)- palladium(I)] dichloromethane solvate [PDF]
, 2002 The dimeric palladium(I) saccharinate complex [Pd₂(sac)₂(dppm)₂], has been characterized as its di¬chloro¬methane solvate, i.e. [Pd₂(C₇H₄NO₃S)₂(C₂₅H₂₂P₂)₂]•CH₂Cl₂.
Chung, Dong C. +2 more
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Journal of Integrative Neuroscience, 2023 Background: Many studies have shown that the levels of homocysteine (Hcy), vitamin B12 (Vit B12), and folate (FA) are abnormal in patients with Parkinson’s disease (PD), but the results have not been consistent. Therefore, we conducted this meta-analysis
Yiti Liu, Maoyuan Gou, Xiaoyan Guo
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On-line PD detection and localization in cross-bonded HV cable systems [PDF]
, 2014 This paper addresses the detection and localization of partial discharge (PD) in crossbonded (CB) high voltage (HV) cables. A great deal has been published in recent years on PD based cable insulation condition monitoring, diagnostics and localization in
Hepburn, Donald M. +5 more
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Simultaneous quantifications of four purine derivatives biomarkers in cow milk by SPE HPLC-DAD
Czech Journal of Food Sciences, 2021 In this study, simultaneous quantification of allantoin, uric acid, xanthine, and hypoxanthine in cow milk by solid phase extraction (SPE) and high performance liquid chromatography-diode array detection (HPLC-DAD) method was perform.
Mihaela Vlassa +2 more
doaj +1 more source
Levodopa-carbidopa intestinal gel therapy in Parkinson’s disease: Procedure complications [PDF]
Romanian Journal of Neurology, 2020 Objectives. Continuous delivery of levodopa-carbidopa intestinal gel (LCIG) represents a gold standard option for the treatment of advanced PD and the benefits of intestinal gel delivery are significative superior from those obtained with available ...
Luminita Celia Popa +4 more
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Mechanistic investigations of bipyrimidine-promoted palladium-catalyzed allylic acetoxylation of olefins [PDF]
, 2009 Several pyridine-like ligands were found to improve Pd(OAc)2-catalyzed allylic oxidation of allylbenzene to cinnamyl acetate by p-benzoquinone in acetic acid.
Bercaw, John E. +2 more
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