Results 61 to 70 of about 3,147,744 (277)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
, 2012 Factorial clustering methods have been developed in recent years thanks to the improving of computational power. These methods perform a linear transformation of data and a clustering on transformed data optimizing a common criterion.
A. Ben-Israel +6 more
core +2 more sources
A pragmatic macroeconomic default risk adjustment in developing countries
South African Journal of Economic and Management SciencesBackground: The expected credit loss (ECL) framework of International Financial Reporting Standards Foundation (IFRS) 9 typically comprises three components: probability of default (PD), loss given default (LGD) and exposure at default (EAD). Among these,
Suben Moodley +2 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
A discrete event simulation model to evaluate the use of community services in the treatment of patients with Parkinson's disease in the United Kingdom. [PDF]
, 2017 BACKGROUND: The number of people affected by Parkinson's disease (PD) is increasing in the United Kingdom driven by population ageing. The treatment of the disease is complex, resource intensive and currently there is no known cure to PD.
Ahmad, R. +4 more
core +6 more sources
Neuropsychiatric Disease and Treatment, 2019 Feng Qiu,1,* Kunyu Wang,1,* Tingting Li,2 Dandan Song,3 Zhiwei Wang,1 Hailing Zhang,4 Jianguo Liu,1 Ming Ren,5 Xiaokun Qi1 1Department of Neurology, Sixth Medical Center of Chinese PLA General Hospital, Beijing, 100048, People’s Republic of China ...
Qiu F +8 more
doaj
Pain assessment in Indian Parkinson's Disease patients using King's Parkinson's Disease pain scale
Annals of Indian Academy of Neurology, 2020 Background: Pain is a common symptom in Parkinson's disease (PD) patients. Scales to rate pain in PD are marred by several flaws, either not being available in other languages or not specific for PD.
Madhuri Behari +4 more
doaj +1 more source
Microorganisms, 2023 The rainbow trout (Oncorhynchus mykiss) is the most important produced species in freshwater within the European Union, usually reared in intensive farming systems.
Lorena Biasini +7 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Peritoneal dialysis in older adults: evaluation of clinical, nutritional, metabolic outcomes, and quality of life [PDF]
, 2018 The number of older adults requiring dialysis is increasing worldwide, whereas the use of peritoneal dialysis (PD) in this population is lower respect to younger patients, despite the theoretical advantages of PD respect to hemodialysis.
Aceto, Paola +10 more
core +1 more source