Results 81 to 90 of about 1,895,251 (293)

Feedback control for deep brain stimulation for motor disorders

Healthcare Technology Letters, 2020
Deep brain stimulation (DBS) is an effective treatment for many people living with Parkinson's disease (PD). Although the primary treatment for PD is based on medications, disease progression eventually leads to inadequate symptom control.
Hugh J. McDermott, Nicholas C. Sinclair
doaj   +1 more source

Pd+, Pd+H+, and Pd+2 on CHA and BEA zeolite

, 2022
The data set contains: Nuclear repulsion energy: xyz coordinates of CHA and BEA energies given in json file (CHA-NRE.json and BEA-NRE.jon) Structures: xyz coordinates of the DFT optimized structures of either Pd-exchanged zeolite (CHA or BEA) or proton compensating zeolite (also CHA and BEA) xyz coordinates are given for the full QM/MM atom and the QM ...
openaire   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

PD-L1 sensitivity and specificity of antibody clone 29E.2A3 for PD-L1.

, 2021
A.Western blot of cell lysates from cultured human breast cancer cell lines known to express (MDA-MB-231) or not to express PD-L1 (MCF-7) using E1L3N Rabbit mAb, confirming the PD-L1 status of these two cell lines. B.
James M. Rae (7876037), Fang Fang (38179), Erin F. Cobain (11707746), Michael Holinstat (599203), Elizabeth P. Darga (10691311), Daniel F. Hayes (2436220), Steven Kregel (289217), Kelley M. Kidwell (8929835), Christina L. Gersch (11707740), Mark Connelly (9202863), Anoop Gill (11707743), Emily M. Dolce (10691310), Costanza Paoletti (10691308), Dafydd G. Thomas (2388385), Martha E. Brown (10691325), Steven Gross (4533598)   +15 more
core   +1 more source

A Brief Review on Laser Therapy in Periodontal and Peri-Implant Healing

Journal of Pharmacy and Bioallied Sciences
Due to the unique properties of light amplification by stimulated emission of radiation (LASER)s, numerous studies have demonstrated favorable postoperative outcomes, including accelerated healing, reduced inflammation, minimal discomfort, and improved ...
Vijay Prakash Bose, Arjun Singh Sodha, Rakesh Jakhar, Mishri Lal Patel, Parvesh Gautam, Pawan Parihar   +5 more
doaj   +1 more source

Purinergic Receptor (P2X7R): A Promising Anti-Parkinson’s Drug Target [PDF]

Advanced Pharmaceutical Bulletin
Purpose: Parkinson’s disease (PD) is the fourth most common neurodegenerative disorder, characterized by degeneration of basal ganglia and a decrease in dopamine levels in the brain.
Saivarshini Magham, M. Lalith Kumar, Praveen Thaggikuppe Krishnamurthy, Neenu Shaji, Aishwarya Reddy Ramakkamma   +4 more
doaj   +1 more source

Total Harmonic Distortion Measurement of 13-level FCML Inverter for SPWM and THIPWM Method [PDF]

Journal of Electrical and Electronics Engineering, 2022
One of the main problems for flying capacitor multilevel (FCML) inverter is the higher value of total harmonic distortion (THD) with number of capacitors and switching devices.
BHADRA Ananta Bijoy
doaj  

PD-1/PD-L pathway and autoimmunity

Autoimmunity, 2005
Programmed cell death 1 (PD-1) was isolated in 1992 by subtractive-hybridization technique, as a molecule whose expression is enhanced by apoptotic stimuli. Since then we have been analyzing the function of PD-1 in the regulation of immune responses. Generation of PD-1 deficient mice, pathophysiological analyses of autoimmune diseases in PD-1 deficient
Taku, Okazaki, Jian, Wang
openaire   +2 more sources

PD-L1/PD-1 Axis in Glioblastoma Multiforme [PDF]

International Journal of Molecular Sciences, 2019
Glioblastoma (GBM) is the most popular primary central nervous system cancer and has an extremely expansive course. Aggressive tumor growth correlates with short median overall survival (OS) oscillating between 14 and 17 months. The survival rate of patients in a three-year follow up oscillates around 10%.
Jakub Litak, Marek Mazurek, Cezary Grochowski, Piotr Kamieniak, Jacek Roliński   +4 more
openaire   +3 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source