Results 11 to 20 of about 13,488 (162)

Association between PD1 mRNA and response to anti-PD1 monotherapy across multiple cancer types [PDF]

open access: yesAnnals of Oncology, 2018
We hypothesized that the abundance of PD1 mRNA in tumor samples might explain the differences in overall response rates (ORR) observed following anti-PD1 monotherapy across cancer types.
L Pare   +2 more
exaly   +3 more sources

Histological diversity of anti-PD1-induced colitis [PDF]

open access: yes, 2022
Aim. Histological data on anti-PD1-associated colitis are limited, while the colitis subtypes are still not clearly defined and different terms are being used. The aim of the study was to explore the histopathology of anti-PD1-induced colitis.
Bamias, Giorgos,   +7 more
core   +2 more sources

Functional and molecular characterization of PD1+ tumor-infiltrating lymphocytes from lung cancer patients. [PDF]

open access: yes, 2022
Antibody-mediated cancer immunotherapy targets inhibitory surface molecules, such as PD1, PD-L1, and CTLA-4, aiming to re-invigorate dysfunctional T cells.
Müller, Stefan   +16 more
core   +1 more source

De ideologische positie van Algemeen Nederlands in Vlaanderen

open access: yesTaal en Tongval: Language Variation in the Low Countries, 2015
The ideological position of Standard Dutch in Flanders: the standard language ideology under pressure? In this paper, the results of a perception study in Flanders are reported. 80 informants were subjected to a qualitative interview, to gain insight in
Chloé Lybaert
doaj   +1 more source

Abstract PD1-01: The Impact of Structural Racism on Breast Cancer Stage at Presentation

open access: yes, 2023
Background: Despite advances in diagnosis and treatment, racial and economic disparities in breast cancer-specific survival persist and this is exacerbated by later stage at presentation.
Hernandez, Alexandra   +5 more
core   +1 more source

Predicting a Stable Dimeric Form of the PD1-PDL1 Complex: Implications for Understanding the PD1 Activation Mechanism

open access: yes
The activation of T cells is typically accompanied by inhibitory mechanisms within which the programmed cell death (PD1) receptor stands out. Upon binding the ligands PDL1 and PDL2, PD1 drives T cells to an unresponsive state called exhaustion ...
Luis F. Ponce (2795155)   +3 more
core   +4 more sources

A triclinic polymorph of bis-(μ-di-tert-butyl-phosphanido)bis-[(di-tert-butyl-phosphane)palladium(I)] [PDF]

open access: yes, 2012
A new polymorph of the title compound, [Pd2(C8H18P)2(C8H19P)2], has been found. It belongs to the triclinic P-1 space group, whereas the known form [Leoni, Sommovigo, Pasquali, Sabatino & Braga (1992 [triangle]), J. Organo­met. Chem.
Lerner, Hans-Wolfram   +5 more
core   +1 more source

PD1 signal transduction pathways in T cells [PDF]

open access: yes, 2017
The use of immune checkpoint inhibitors for the treatment of cancer is revolutionizing oncology. Amongst these therapeutic agents, antibodies that block PD-L1/PD1 interactions between cancer cells and T cells are demonstrating high efficacies and low ...
Arasanz, H   +13 more
core   +1 more source

mprzedborski/ex-vivo-PD1-blockade:

open access: yes, 2021
This is the code for running simulations for the manuscript "Integrating an ex vivo human tumor model with systems biology for the study of PD-1 blockade response dynamics in head and neck squamous cell carcinoma (HNSCC)", authored by: Munisha Smalley ...
mprzedborski
core   +1 more source

cis-Dichloridobis(dimethoxyphenylphosphine)palladium(II)

open access: yes, 2010
The title compound, [PdCl2(C8H11O2P)(2)], has a comparable structure to those of related palladium dichloride complexes containing trimethyl phosphinite and methyl diphenyl phosphinite.
Woollins, J. Derek   +5 more
core   +1 more source

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