Results 31 to 40 of about 13,488 (162)
Objective: To compare the inhibition of LAG3-PD1 versus the inhibition of CTLA-4-PD1 in patients with previously untreated advanced melanoma. Methods: The individual participant data (IPD) were extracted from the KM plots using a graphical reconstructive
Chen, Guo-Ming +19 more
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This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
Australian Red Cross Society, National Office
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Purpose Anti-programmed cell death protein 1 (PD1)±anti-cytotoxic T-lymphocyte associated protein 4 (CTLA4) immune checkpoint inhibitors (ICIs) are standard therapeutic options for metastatic melanoma.
David Hogg +12 more
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PD1 inhibitor induced inverse lichenoid eruption: a case series
The increased use of monoclonal antibodies that target the immune checkpoint T cell receptor programmed death-1 (PD1) to treat numerous solid tumors has led to several reports describing associated cutaneous adverse events.
Garg, Vaibhav +4 more
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We provide evidence here from loss-of-function studies in mice and gain-of-function studies in human cells (1, 2) which demonstrate control of PD1, encoded by PDCD1, by the NLR (nucleotide-binding oligomerization domain-like receptor) family protein NOD2.
Shahan Mamoor
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Regulatory T lymphocytes (T-reg) play a fundamental importance in modulating the relative balance between inflammation and immune tolerance, and alterations of these cells are observed in inflammatory diseases.
A. Gatti +15 more
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Clinical significance of PD1 and PDL1 in human breast cancer [PDF]
Background/Aim: Programmed death 1 (PD1) and its ligand programmed death ligand 1 (PDL1) form a pathway which when activated is thought to result in suppression of antitumor adaptive responses, influencing antitumor immunity.
Owen, Sioned +6 more
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A Comparative Grammar of the Early Germanic Languages
Fulk’s Comparative Grammar offers an overview of and bibliographical guide to the study of the phonology and the inflectional morphology of the earliest Germanic languages, with particular attention to Gothic, Old Norse / Icelandic, Old English, Old ...
R.D. Fulk
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This book aims to locate and draw out resonances of impressionism in Swedish and Finland-Swedish prose at the end of the nineteenth century, a field hitherto overlooked in the critical debate on literary impressionism.
Storskog, Camilla, Camilla Storskog
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Agonistic CD40 mAb-driven IL12 reverses resistance to anti-PD1 in a T-cell-rich tumor
The durability and efficacy of anti-human PD1 monoclonal antibodies (PD1 mAb) vary across different malignancies. Although an absence of tumor-infiltrating cytotoxic T lymphocytes has been identified as a cause for resistance to PD1 mAb, the presence of ...
Stephen J. Blake +15 more
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