Results 171 to 180 of about 2,849 (260)

Designer Dynamic DNA Nanoaggregate in Living Cell for Mitochondrial Energy Restriction

Advanced Science, EarlyView.
This study presents the Tech‐tetrahedron, a designer dynamic DNA nanoaggregate engineered for precise mitochondrial energy restriction. Its trinity‐functionalized design integrates navigable unit, telomerase‐activated latch, and self‐assembly module.
Ruijia Deng, Jing Sheng, Ben Niu, Wenjuan Fu, Yingjie Yang, Zuowei Xie, Shuang Xie, Yunxuan He, Meilin Gong, Jue Wang, Yan Pi, Ming Chen, Kai Chang   +12 more
wiley   +1 more source

An immunoassay for the quantification of phosphorylated α-synuclein at serine 129 in human cerebrospinal fluid. [PDF]

Bioanalysis
Silva AM, Hickford ES, Cutler P.
europepmc   +1 more source

One‐Step Preparation of Lanthanide‐Doped Polyurea Multicolor Microspheres for Versatile Fluorescent Applications

Advanced Science, EarlyView.
Lanthanide‐doped polyurea microspheres are prepared via a facile one‐step precipitation polymerization. They exhibit strong hydrogen‐bonding and coordination interactions with excellent properties, including multicolor emission, high quantum yield (75.3%), remarkable stability, redispersibility, and biocompatibility.
Guiyu Zhang, Xiaoxia Yu, Xinhui Wang, Xiang Zheng Kong, Xiangling Gu, Jitao Liu, Shusheng Li, Xiaoli Zhu, Lianbao Cao, Xubao Jiang   +9 more
wiley   +1 more source

Genome-wide identification and expression analysis under selenium stress of glutaredoxin system genes in Cardamine hupingshanensis. [PDF]

BMC Plant Biol
Xue H, Li Y, Xiao J, Lu Y, Xiang Z, Hou Z, Zhou Y, Tang Q.   +7 more
europepmc   +1 more source

Toward Precision Cancer Immunotherapy

Advanced Science, EarlyView.
Shuang Tang, Jean J. Zhao, Ada Hang‐Heng Wong   +2 more
wiley   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

Long COVID involves activation of proinflammatory and immune exhaustion pathways. [PDF]

Nat Immunol
Aid M, Boero-Teyssier V, McMahan K, Dang R, Doyle M, Belabbaci N, Borducchi E, Collier AY, Mullington J, Barouch DH.   +9 more
europepmc   +1 more source

Uncertainty‐Aware Deep Ensembles for Robust and Reliable Chemical Sensor Arrays

Advanced Science, EarlyView.
A reliability‐aware electronic nose is developed using photothermally anchored metal‐catalyst decorated metal oxide nanofiber sensor arrays combined with deep ensemble learning. Diverse catalytic nanofiber channels generate gas‐specific response patterns, enabling selective identification and quantification of sulfur‐containing gases.
Sungwoo Eo, Ji‐Hwan Eum, Suk‐Jeong Kwon, Minji Sagong, Dongchan Kim, Dong‐Ha Kim   +5 more
wiley   +1 more source

Cytotoxic Potential Evaluation of Innovative Pressurised Cyclic Solid-Liquid Extracts from <i>Withania somnifera</i>. [PDF]

Plants (Basel)
Culurciello R, Power K, Esposito S, Di Nardo I, Landi S, De Vico G, Palatucci D, Pizzo E, Naviglio D, Zarrelli A.   +9 more
europepmc   +1 more source

Embedded Direct‐Written Organic Micro‐TEGs for High‐Efficiency Skin‐Heat Harvesting

Advanced Electronic Materials, EarlyView.
A finite‐element–guided design of direct‐written organic micro‐thermoelectric generators is presented for efficient skin‐heat harvesting. Embedding PEDOT:PSS/PBFDO thermoelectric legs within flexible substrates suppresses interfacial heat losses and enhances vertical heat flow.
Milad Jabri, Saeed Masoumi, Dimitrios Paparas, Mónica Acuautla, Luigi Giuseppe Occhipinti   +4 more
wiley   +1 more source