Results 1 to 10 of about 299,451 (168)

pdb-care (PDB CArbohydrate REsidue check): a program to support annotation of complex carbohydrate structures in PDB files [PDF]

open access: yesBMC Bioinformatics, 2004
Background Carbohydrates are involved in a variety of fundamental biological processes and pathological situations. They therefore have a large pharmaceutical and diagnostic potential.
von der Lieth Claus-W, Lütteke Thomas
doaj   +3 more sources

Seeing the PDB [PDF]

open access: yesJournal of Biological Chemistry, 2021
Ever since the first structures of proteins were determined in the 1960s, structural biologists have required methods to visualize biomolecular structures, both as an essential tool for their research and also to promote 3D comprehension of structural results by a wide audience of researchers, students, and the general public.
Jane S. Richardson   +2 more
openaire   +2 more sources

Produk Domestik Bruto dan Kurs Sebagai Determinan Impor Pupuk Indonesia

open access: yesSorot, 2021
Impor pupuk dilakukan untuk memenuhi kebutuhan kebutuhan pupuk. Penelitian ini bertujuan untuk menganalisis pengaruh PDB dan nilai tukar sebagai determinan impor pupuk di Indonesia.
Mardiana Mardiana   +2 more
doaj   +1 more source

The PDB and the ribosome [PDF]

open access: yesJournal of Biological Chemistry, 2021
This essay, which was written to commemorate the 50th anniversary of the Protein Data Bank, opens with some comments about the intentions of the scientists who pressed for its establishment and the nature of services it provides. It includes a brief account of the events that resulted in the determination of the crystal structure of the large ribosomal
openaire   +2 more sources

Comparative Stability Study of Polysorbate 20 and Polysorbate 80 Related to Oxidative Degradation

open access: yesPharmaceutics, 2023
The surfactants polysorbate 20 (PS20) and polysorbate 80 (PS80) are utilized to stabilize protein drugs. However, concerns have been raised regarding the degradation of PSs in biologics and the potential impact on product quality.
Benedykt Kozuch   +5 more
doaj   +1 more source

Antimicrobial Preservatives for Protein and Peptide Formulations: An Overview

open access: yesPharmaceutics, 2023
Biological drugs intended for multi-dose application require the presence of antimicrobial preservatives to avoid microbial growth. As the presence of certain preservatives has been reported to increase protein and peptide particle formation, it is ...
Luisa Stroppel   +6 more
doaj   +1 more source

PENGUJIAN EKSISTENSI ENVIRONMENTAL KUZNETS CURVE DI INDONESIA

open access: yesJurnal Lebesgue, 2021
Tujuan studi adalah untuk menguji eksistensi fenomena environmental Kuznets Curve (EKC). Metode yang digunakan dalam  penelitian ini adalah metode regresi kuadratik yng diestimasi dengan ordinary least square dengan terlebih dahulu merekonstruksi varibel
Muhammad Fajar, Hariyanto
doaj   +1 more source

Alternative Excipients for Protein Stabilization in Protein Therapeutics: Overcoming the Limitations of Polysorbates

open access: yesPharmaceutics, 2022
Given their safety and efficiency in protecting protein integrity, polysorbates (PSs) have been the most widely used excipients for the stabilization of protein therapeutics for years.
Angel J. Castañeda Ruiz   +6 more
doaj   +1 more source

PDB-Tools Web: A user-friendly interface for the manipulation of PDB files [PDF]

open access: yesProteins: Structure, Function, and Bioinformatics, 2020
Abstract The Protein Data Bank (PDB) file format remains a popular format used and supported by many software to represent coordinates of macromolecular structures. It however suffers from drawbacks such as error‐prone manual editing. Because of that, various software toolkits have been developed to facilitate its
Jiménez‐García, Brian   +4 more
openaire   +4 more sources

Photo-Oxidation of Therapeutic Protein Formulations: From Radical Formation to Analytical Techniques

open access: yesPharmaceutics, 2021
UV and ambient light-induced modifications and related degradation of therapeutic proteins are observed during manufacturing and storage. Therefore, to ensure product quality, protein formulations need to be analyzed with respect to photo-degradation ...
Elena Hipper   +4 more
doaj   +1 more source

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