Results 11 to 20 of about 381,553 (352)

pdb-care (PDB CArbohydrate REsidue check): a program to support annotation of complex carbohydrate structures in PDB files [PDF]

BMC Bioinformatics, 2004
Background Carbohydrates are involved in a variety of fundamental biological processes and pathological situations. They therefore have a large pharmaceutical and diagnostic potential.
von der Lieth Claus-W, Lütteke Thomas
doaj   +6 more sources

RCSB Protein Data Bank (PDB): Driving Research and Education Using Experimentally-Determined Structures and Computed Structure Models from Artificial Intelligence/Machine Learning [PDF]

Structural Dynamics
The 2024 Nobel Prize in Chemistry was awarded to David Baker, Demis Hassabis, and John Jumper for computational protein design and protein structure prediction.
Yuhe Liang, Christine Zardecki, RCSB PDB Team   +2 more
doaj   +2 more sources

Seeing the PDB [PDF]

Journal of Biological Chemistry, 2021
Ever since the first structures of proteins were determined in the 1960s, structural biologists have required methods to visualize biomolecular structures, both as an essential tool for their research and also to promote 3D comprehension of structural ...
J. Richardson, D. Richardson, D. Goodsell   +2 more
semanticscholar   +3 more sources

PDB-Tools Web: A user-friendly interface for the manipulation of PDB files [PDF]

Proteins: Structure, Function, and Bioinformatics, 2020
The Protein Data Bank (PDB) file format remains a popular format used and supported by many software to represent coordinates of macromolecular structures. It however suffers from drawbacks such as error‐prone manual editing.
B. Jiménez-García, Jmc Teixeira, M. Trellet, J. Rodrigues, A. Bonvin   +4 more
semanticscholar   +5 more sources

PDB-Dev: a Prototype System for Depositing Integrative/Hybrid Structural Models

Structure, 2017
Burley et al. (leadership of the Worldwide PDB [wwPDB] Partnership [wwpdb.org] and the wwPDB Integrative/Hybrid Methods Task Force) announce public release of a prototype system for depositing integrative/hybrid structural models, PDB-Development (PDB ...
S. Burley, G. Kurisu, J. Markley, Haruki Nakamura, S. Velankar, H. Berman, A. Sali, T. Schwede, J. Trewhella   +8 more
semanticscholar   +2 more sources

The PDB and the ribosome [PDF]

Journal of Biological Chemistry, 2021
This essay, which was written to commemorate the 50th anniversary of the Protein Data Bank, opens with some comments about the intentions of the scientists who pressed for its establishment and the nature of services it provides. It includes a brief account of the events that resulted in the determination of the crystal structure of the large ribosomal
openaire   +2 more sources

Alternative Excipients for Protein Stabilization in Protein Therapeutics: Overcoming the Limitations of Polysorbates

Pharmaceutics, 2022
Given their safety and efficiency in protecting protein integrity, polysorbates (PSs) have been the most widely used excipients for the stabilization of protein therapeutics for years.
Angel J. Castañeda Ruiz, Maryam A. Shetab Boushehri, Tamara Phan, Stefan Carle, Patrick Garidel, Julia Buske, Alf Lamprecht   +6 more
doaj   +1 more source

RCSB Protein Data Bank: Celebrating 50 years of the PDB with new tools for understanding and visualizing biological macromolecules in 3D

Protein Science, 2021
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), funded by the US National Science Foundation, National Institutes of Health, and Department of Energy, has served structural biologists and Protein Data Bank (PDB ...
S. Burley, Charmi Bhikadiya, Chunxiao Bi, Sebastian Bittrich, Li Chen, G. Crichlow, Jose M. Duarte, S. Dutta, M. Fayazi, Zu-Kang Feng, J. Flatt, S. Ganesan, D. Goodsell, Sutapa Ghosh, Rachel Kramer Green, Vladimir Guranovic, Jeremy Henry, B. Hudson, C. Lawson, Yuhe Liang, Robert Lowe, E. Peisach, Irina Persikova, Dennis W. Piehl, Yana Rose, A. Sali, J. Segura, Monica R. Sekharan, C. Shao, Brinda K. Vallat, Maria Voigt, J. Westbrook, S. Whetstone, Jasmine Y. Young, C. Zardecki   +34 more
semanticscholar   +1 more source

RNAsolo: a repository of cleaned PDB-derived RNA 3D structures

Bioinform., 2022
Motivation The development of algorithms dedicated to RNA three-dimensional (3D) structures contributes to the demand for training, testing and benchmarking data.
B. Adamczyk, M. Antczak, M. Szachniuk
semanticscholar   +1 more source

Photo-Oxidation of Therapeutic Protein Formulations: From Radical Formation to Analytical Techniques

Pharmaceutics, 2021
UV and ambient light-induced modifications and related degradation of therapeutic proteins are observed during manufacturing and storage. Therefore, to ensure product quality, protein formulations need to be analyzed with respect to photo-degradation ...
Elena Hipper, Michaela Blech, Dariush Hinderberger, Patrick Garidel, Wolfgang Kaiser   +4 more
doaj   +1 more source