Results 171 to 180 of about 326,099 (315)

Orthogonal Ionic Liquid‐Based Extraction Strategy Enables Amyloid‐Specific Profiling of Aggregate Proteome

Advanced Science, EarlyView.
An orthogonal ionic‐liquid extraction (Orth‐iEA) enables selective isolation of amyloid fibrils. TMGBF4 disrupts hydrogen‐bonded β‐sheet networks to solubilize amyloid aggregates, whereas C12ImCl interacts with hydrophobic regions of non‐amyloid proteins.
Shiying Zheng, Ye Liu, Bowen Zhong, Huiying Chu, Zhou Gong, Baofeng Zhao, Mengchun Cheng, Zhen Liang, Yukui Zhang, Qun Zhao, Lihua Zhang   +10 more
wiley   +1 more source

Refinements on the Complementary PDB Construction Mechanism

CoRR
Pattern database (PDB) is one of the most popular automated heuristic generation techniques. A PDB maps states in a planning task to abstract states by considering a subset of variables and stores their optimal costs to the abstract goal in a look up table.
openaire   +2 more sources

Retraction: In silico investigation of novel Plasmodium Falciparum glycogen synthase kinase (pfGSk3β) inhibitors for the treatment of malaria infection. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Structural basis of human clamp sliding on DNA

, 2021
Crehuet, R., Onesti, S., Merino, N., De Biasio, A., Barrera-Vilarmau, S., De March, Matteo, Blanco-Silva, Francisco J.   +6 more
core   +1 more source

AlfB fucosidase in complex with Fucose [X-RAY DIFFRACTION 2.25 Å]

Usage Policies The wwPDB policy states that data files contained in the PDB archive are available under the CC0 1.0 Universal (CC0 1.0) Public Domain DedicatioMinisterio de Ciencia e Innovacion (MCIN)9HYJ.pdbPeer ...
Marina, Alberto, Gallego del Sol, Francisca   +1 more
core   +1 more source

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

Advanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa, Jingjun Mo, Xiaotong Diao, Feng Xie, Tingting Wang, Haowen Zhao, Dalei Wu, Rolf Müller, Chengzhang Fu   +8 more
wiley   +1 more source

Prediction of pre- and postfusion conformations of class I fusion proteins with AlphaFold2. [PDF]

PLoS One
Gülesen S, Most V, Schoeder CT, Meiler J.   +3 more
europepmc   +1 more source

Crystal structure of CNG mimicking NaK mutant, NaK-ETPP, Cs+ complex

, 2021
Onesti, S., Napolitano, L. M. R., De March, Matteo   +2 more
core   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Predicting unknown binding sites for transition-metal-based compounds in proteins. [PDF]

PLoS One
Levy A, Rothlisberger U.
europepmc   +1 more source