Results 171 to 180 of about 381,553 (352)

RCSB Protein Data Bank: supporting research and education worldwide through explorations of experimentally determined and computationally predicted atomic level 3D biostructures

IUCrJ
The Protein Data Bank (PDB) was established as the first open-access digital data resource in biology and medicine in 1971 with seven X-ray crystal structures of proteins.
Stephen K. Burley, Dennis W. Piehl, Brinda Vallat, Christine Zardecki   +3 more
doaj   +1 more source

PDB-REPRDB: a database of representative protein chains from the Protein Data Bank (PDB

, 2001
PDB-REPRDB is a database of representative protein chains from the Protein Data Bank (PDB). Started at the Real World Computing Partnership (RWCP) in August 1997, it developed to the present system ...
Tamotsu Noguchi, Yutaka Akiyama
core  

PDB Hadoop software

, 2018
Code used to deploy high throughput analysis of PDB using ...
Jamie Alnasir (4555150), Hugh Shanahan (4553653)   +1 more
core   +1 more source

Somatic Evolution of a Germline Antibody Expands its Breadth to Neutralize Early SARS‐CoV‐2 Omicron Variants

Advanced Science, EarlyView.
Engineering of the 148‐germline (148‐GL) antibody reveals a roadmap for overcoming SARS‐CoV‐2 viral escape. By introducing four specific somatic hypermutations, the resulting 148‐M4 variant restores potent neutralization against Omicron BA.1 and BA.4/5.
Huibin Lv, Ziqi Feng, Qi Wen Teo, Chunke Chen, Akshita B. Gopal, Danbi Choi, Timothy J. C. Tan, Yun Sang Tang, Lewis Siu, Armita Nourmohammad, Roberto Bruzzone, Ian A. Wilson, Meng Yuan, Nicholas C. Wu, Chris K. P. Mok   +14 more
wiley   +1 more source

The 'new' PDB [PDF]

Nature Structural Biology, 1998
openaire   +2 more sources

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

A general strategy for discovery of inhibitors and activators of RING and U-box E3 ligases with ubiquitin variants

, 2017
This record links to 4 protein structures determined by x-ray crystallography, deposited in the RCSB ...
Huang, Danny, Nakasone, Mark, Sibbet, Gary, Gabrielsen, Mads, Smith, Brian, Zhang, Wei, Sidhu, Sachdev, Buetow, Lori, Ahmed, Syed   +8 more
core  

Docking structure between (PDB 2R22) and SFN.

, 2015
(A) Surface representation of (PDB 2R22) complexes with SFN (Display side). (A') Close up view of (PDB 2R22) complexes with SFN. (B) Surface representation of (PDB 2R22) complexes with SFN (Display top).
Farzaneh Abassi Joozdani (747652), Shohreh Nafisi (489871), Faramarz Yari (747653), Parvaneh Abassi Joozdani (747654)   +3 more
core   +1 more source

DDX3x Regulates NINJ1 Transcription via Histone Lactylation in Sepsis Associated‐Acute Kidney Injury

Advanced Science, EarlyView.
This study identifies a potential therapeutic approach for sepsis‐associated acute kidney injury (SA‐AKI). We found that during SA‐AKI, reduced expression of DDX3x in renal tubular epithelial cells mediates histone delactylation, which in turn upregulates NINJ1 transcription and triggers tubular cell death. Conversely, Odetiglucan confers protection by
Hongyu Liang, Jihong Jiang, Huanxin Yin, Chunyan Liu, Hongjun Huang, Yan Luo, Minmin Zhu, Qiuyun Wang   +7 more
wiley   +1 more source

Community structure of highly efficient phenol degrading bacteria and phenol metabolites

Gongye shui chuli
By using activated sludge from the anaerobic tank of a coking plant, a highly efficient phenol-degrading bacterial (PDB) community was successfully obtained through separation and domestication, and its effect on microbial degradation of phenol was ...
XU Lingli, LIU Yuxiang, DONG Jing, REN Li, WANG Wenjun, YUAN Ke   +5 more
doaj   +1 more source