Results 131 to 140 of about 33,386 (268)

Practical Day‐Ahead Gas Generator Dispatch Optimisation for Enhancing the Reserved Capacity

IET Smart Energy Systems, EarlyView.
Practical day‐ahead gas generator dispatch optimisation model is proposed to enhance the system reserved capacity. ABSTRACT In order to reduce carbon dioxide emissions, traditional coal‐fired power generation has been strictly limited in China recently, which has led to the problem of reserved capacity shortage. As one of the critical east provinces of
Shengyuan Liu, Yicheng Jiang, Wei Gu, Wenduo Sun, Bin Feng, Gang Huang, Yunchu Wang   +6 more
wiley   +1 more source

The psychological compensation effect: perceived digital exclusion, perceived lack of control, and their impact on consumption behaviors of elderly tourists. [PDF]

Front Psychol
Shi J, Li Y, Deng W.
europepmc   +1 more source

Integrating infection intensity and aggregation into the dynamics of pathogens with within‐host replication

Journal of Animal Ecology, EarlyView.
We bridge micro‐ and macroparasite theory with a model tracking pathogen load heterogeneity. By incorporating load‐dependent mortality and within‐host pathogen growth, we show how pathogen load aggregation alters disease prevalence, host suppression effects, and virulence evolution, providing insights for managing complex infectious disease like ...
Ruijiao Sun, Jason Cosens Walsman, Mark Wilber, Cheryl J. Briggs   +3 more
wiley   +1 more source

Abscisic acid binds to an <i>Arabidopsis thaliana</i> phosphodiesterase and tunes its activity. [PDF]

Front Plant Sci
Kwiatkowski M, Kozakiewicz-Piekarz A, Bi C, Wong A, Jaworski K, Irving H, Gehring C.   +6 more
europepmc   +1 more source

What Causes Geographic Variation in Drug Prescribing? Evidence from Physician Migration

The RAND Journal of Economics, EarlyView.
ABSTRACT In this article, we examine the importance of individual physicians in explaining the significant variation in prescription drug spending in Medicare Part D. By tracking prescribing behavior before and after physician relocations, we find that movers' prescribing converges toward the average of their new location.
David Beheshti, Seth Neller
wiley   +1 more source

Rates and Predictors of Persistent LUTS Medication Use After Laser Enucleation of the Prostate. [PDF]

Low Urin Tract Symptoms
Filzmayer M, Traumann MI, Humke C, Müller MJ, Mandel PC, Kluth LA, Becker A, Chun FK, Kosiba M.   +8 more
europepmc   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

A fission yeast-based platform for nematode PDE inhibitor discovery. [PDF]

Cell Signal
Bibeau S, Chen N, Sutoris H, Ly J, Eberhard J, Hubbell SM, Banda E, Povh E, Anindya CS, Berwanger MR, Sinise SE, Zhang X, Morken JP, Galande KK, Cote RH, Dranchak PK, Inglese J, Hoffman CS.   +17 more
europepmc   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source