Results 111 to 120 of about 4,135 (194)

Correction to: An insight into reactivity and bioactivity properties of quorum sensing peptides against PDE10A: a computational peptidology approach [PDF]

open access: bronze, 2022
Bhargav Shreevatsa   +10 more
openalex   +1 more source

PNU-120596, a positive allosteric modulator of α7 nicotinic acetylcholine receptors, reverses a sub-chronic phencyclidineinduced cognitive deficit in the attentional set-shifting task in female rats [PDF]

open access: yes, 2011
yThe α7 nicotinic acetylcholine receptors (nAChRs) have been highlighted as a target for cognitive enhancement in schizophrenia. Adult female hooded Lister rats received sub-chronic phencyclidine (PCP) (2mg/kg) or vehicle i.p.
Anne S Lesage   +9 more
core   +1 more source

Genomic characterization of individuals presenting extreme phenotypes of high and low risk to develop tobacco‐induced lung cancer

open access: yesCancer Medicine, 2018
Single nucleotide polymorphisms (SNPs) may modulate individual susceptibility to carcinogens. We designed a genome‐wide association study to characterize individuals presenting extreme phenotypes of high and low risk to develop tobacco‐induced non‐small ...
Juan Pablo Fusco   +26 more
doaj   +1 more source

Pivotal role of PDE10A in the integration of dopamine signals in mice striatal D1 and D2 medium-sized spiny neurones [PDF]

open access: gold, 2021
Élia Mota   +4 more
openalex   +1 more source

Family-Wide Dysregulation of Phosphodiesterases Alters cAMP/cGMP Microdomains in Thoracic Aortic Aneurysm

open access: yesJournal of Cardiovascular Development and Disease
Background: Thoracic aortic aneurysm (TAA) is driven by complex molecular mechanisms beyond size thresholds, yet the role of cyclic nucleotide metabolism remains unclear.
Dimitrios E. Magouliotis   +7 more
doaj   +1 more source

PDE10A Inhibition Reduces the Manifestation of Pathology in DMD Zebrafish and Represses the Genetic Modifier PITPNA [PDF]

open access: bronze, 2020
Matthias Lambert   +7 more
openalex   +1 more source

An efficient approach to screening epigenome-wide data

open access: yes, 2016
Screening cytosine-phosphate-guanine dinucleotide (CpG) DNA methylation sites in association with some covariate(s) is desired due to high dimensionality.
Karmaus, Wilfried J.J.   +4 more
core   +2 more sources

N-Methylanilide and N-methylbenzamide derivatives as phosphodiesterase 10A (PDE10A) inhibitors

open access: green, 2013
John Paul Kilburn   +7 more
openalex   +1 more source

Focal Spot, Summer/Fall 2008 [PDF]

open access: yes, 2008
https://digitalcommons.wustl.edu/focal_spot_archives/1109/thumbnail ...

core   +1 more source

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