Results 131 to 140 of about 4,135 (194)

Molecular Imbalances Between Striosome and Matrix Compartments Characterize the Pathogenesis and Pathophysiology of Huntington's Disease Model Mouse. [PDF]

Int J Mol Sci
Morigaki R, Yoshida T, Fujikawa J, Crittenden JR, Graybiel AM.   +4 more
europepmc   +1 more source

PATH-06. Loss of PDE10A is associated with brain metastases and other adverse clinicopathologic features of gastrointestinal carcinoma [PDF]

Sumaita Arowa, Nicholas Nuechterlein, Vinny Ha, Allison Shelbourn, Ashis Chowdhury, Yeshavanth Banasavadi‐Siddegowda, Jerzy Lasota, Markku Miettinen, Patrick J. Cimino   +8 more
openalex   +1 more source

Synthesis of Fluorine-Containing Phosphodiesterase 10A (PDE10A) Inhibitors and the In Vivo Evaluation of F-18 Labeled PDE10A PET Tracers in Rodent and Nonhuman Primate

, 2015
Junfeng Li, Xiang Zhang, Hongjun Jin, Jinda Fan, Hubert Flores, Joel S. Perlmutter, Zhude Tu   +6 more
openalex   +1 more source

A phase 1 study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of TAK-063, a selective PDE10A inhibitor [PDF]

, 2016
Max Tsai, Lambros Chrones, Jinhui Xie, Hakop Gevorkyan, Thomas A. Macek   +4 more
openalex   +1 more source

PDE10A Inhibition Reduces NLRP3 Activation and Pyroptosis in Sepsis and Nerve Injury. [PDF]

Int J Mol Sci
Berk BC, Chávez CL, George Hsu C.
europepmc   +1 more source

The Emerging Role of Phosphodiesterase Inhibitors in Fragile X Syndrome and Autism Spectrum Disorder. [PDF]

Pharmaceuticals (Basel)
Thomas SD, Mohammed HA, Hamad MIK, Oz M, Statsenko Y, Sadek B.   +5 more
europepmc   +1 more source

N-Methyl-D-Aspartate (NMDA) Receptor Encephalitis Without Electroencephalogram Abnormalities or Cerebrospinal Fluid Pleocytosis Associated With a Tiny Ovarian Teratoma: A Case Report. [PDF]

Cureus
Miyashita A, Takaoka K, Lachar J.
europepmc   +1 more source

N-Acylhydrazones as inhibitors of PDE10A

, 2011
Jennifer L. Gage, René Onrust, Derek Johnston, Andrew P. Osnowski, Wendy Macdonald, Lee Mitchell, László Ürögdi, Alex Rohde, Kevin Harbol, Sasha Gragerov, György Dormán, T. S. Wheeler, Vince Florio, Neil S. Cutshall   +13 more
openalex   +1 more source

Radiation dosimetry of [¹¹C]TZ1964B as determined by whole-body PET imaging of nonhuman primates. [PDF]

EJNMMI Res
Maiti B, Goldman NL, Hamdi M, Lenox-Krug J, Karimi M, Moerlein SM, Laforest R, Huang T, Tu Z, Perlmutter JS, Norris SA.   +10 more
europepmc   +1 more source

ADCY5-related movement disorders: Frequency, disease course and phenotypic variability in a cohort of paediatric patients [PDF]

, 2017
Bhatia, KP, Bonakis, A, Carecchio, M, Dinopoulos, A, Fusco, C, Garavaglia, B, Iodice, A, Jankovic, J, Mencacci, NE, Monti, V, Nardocci, N, Panteghini, C, Pons, R, R'Bibo, L, Stamelou, M, Stefanis, L, Veneziano, L, Wood, N, Zibordi, F, Zorzi, G   +19 more
core   +2 more sources