Results 81 to 90 of about 569,072 (335)

Islet Amyloid Polypeptide Modelled to Simulate Diabetes Co‐Oligomerized with β‐Amyloid 1‐42 Reproducing the Pathological Cascade of Alzheimer's Disease in Human Cerebral Organoids

Advanced Science, EarlyView.
Human islet amyloid polypeptide (hIAPP) was used to mimic T2DM, and Aβ42‐hIAPP co‐oligomers were delivered into the human mature cerebral organoids (COs), which reproduce typical AD pathology and significant neuronal death more closely resembling that of AD patients.
Jin Yan, Zhimeng Tang, Yanyu Luo, Bin Liu, Xinxin Huang, Jun Wei, Feng Yue   +6 more
wiley   +1 more source

Decoding Trap States in Working 2D Perovskite Multi‐Functional Devices

Advanced Science, EarlyView.
Illustration of the photoluminescence spectrum and energy‐level landscape governing trap‐mediated carrier dynamics in 2D F‐PEAI photodetectors. A novel approach capturing dynamic trap occupation and retrapping in devices under operating conditions, directly links defect energetics to carrier transport and enhanced photoresponse in multifunctional ...
Ioannis Leontis, Karl Jonas Riisnaes, Hoi Tung Lam, Rosanna Mastria, Luisa De Marco, Annalisa Coriolano, Steven Hepplestone, Monica Felicia Craciun, Saverio Russo   +8 more
wiley   +1 more source

Pharmacokinetic/pharmacodynamic issues for optimizing treatment with beta-lactams of Gram-negative infections in critically ill orthotopic liver transplant recipients: a comprehensive review

Frontiers in Antibiotics
Orthotopic liver transplant (OLT) represents the standard of care for managing patients affected by end-stage and life-threatening liver diseases.
Milo Gatti, Milo Gatti, Federico Pea, Federico Pea   +3 more
doaj   +1 more source

Can Program Explanations Save the Causal Efficacy of Beliefs? [PDF]

, 2003
Frank Jackson and Philip Pettit offered the "program\ud explanation account� (PEA) in order to vindicate the causal\ud relevance of mental states such as beliefs.
Walter, Sven
core  

Electric Field Determination in DC Polymeric Power Cable in the Presence of Space Charge [PDF]

, 2007
The pulsed electroacoustic (PEA) technique was used to perform space charge measurements in polymeric power cables. However, for a practical dc power cable the electric field is affected by conductivity of the material, which is a function of both ...
Chen, George, Choo, Wilson
core   +1 more source

Structure‐Function Integration in 2D Hybrid Perovskite for Fast Neutron and Gamma Ray Discrimination

Advanced Science, EarlyView.
Using an in situ seed‐assisted cooling method, large (28 × 7 × 3 mm3) (GABA)2PbBr4 single crystals are grown, featuring hydrogen‐rich organic layers and a dense PbBr4 framework. This architecture enables efficient γ‐ray absorption, fast‐neutron sensitivity, and clear n/γ pulse‐shape discrimination (FOM up to 1.74), highlighting its potential as a ...
Yingming Wang, Lingyan Xu, Chongqi Liu, Lu Liang, Binghui Zhang, Zhentao Qin, Lixiang Lian, Wei Zheng, Yanyan Lei, Qinzeng Hu, Shuai Song, Chaopeng Mi, Tao Wang, Yadong Xu, Gangqiang Zha, Wanqi Jie   +15 more
wiley   +1 more source

Green Production of Anionic Surfactant Obtained from Pea Protein [PDF]

, 2011
A pea protein isolate was hydrolyzed by a double enzyme treatment method in order to obtain short peptide sequences used as raw materials to produce lipopeptides-based surfactants.
A Clemente, A Tsoukala, A Villanueva, AF Dexter, Bénédicte Portet, C Megias, C Rondel, Caroline Rondel, CN Mulligan, D Kitamoto, EA Pena-Ramos, FM Netto, Françoise Silvestre, H Frister, H Schägger, Isabelle Alric, J Vioque, Jean-François Blanco, JS Hamada, JY Lee, K Pommer, K Yasamatsu, LA Graaf De, LM Humiski, M Dall Aaslyng, M Karamac, M Le Gall, MC Marquez, MPC Silvestre, MR Infante, P Anastas, PM Nielsen, R Amarowicz, R Sanchez-Vioque, R Sanchez-Vioque, R Sinha, RT Swank, S Jung, TS Padmashree, UK Laemmli, Zéphirin Mouloungui   +40 more
core   +2 more sources

Nitrogen‐Boosted H2O2 Production of Arginine‐Polyphenol Nanozyme Drives Oxidative Eustress for Hair Regeneration

Advanced Science, EarlyView.
PEA nanoenzymes are assembled from L‐arginine and EGCG. The nitrogen element in arginine enhances the thermodynamic feasibility of H2O2 production through PEA's oxygen reduction catalysis, enabling nitrogen‐dependent H2O2 release. Intradermal delivery of PEA via microneedles promotes efficient H2O2 synthesis, thereby stimulating regrowth in telogen ...
Yifei Wang, Yaojia Yang, Aoxue Wang, Chen Shen, Shenliang Tan, Changsheng Liu, Yuzheng Zhao, Xue Qu   +7 more
wiley   +1 more source

Pharmacokinetic-pharmacodynamic influence of N-palmitoylethanolamine, arachidonyl-2′-chloroethylamide and WIN 55,212-2 on the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice [PDF]

, 2016
We evaluated the effects of ACEA (selective cannabinoid (CB)1 receptor agonist), WIN 55,212-2 mesylate (WIN; non-selective CB1 and CB2 receptor agonist) and N-palmitoylethanolamine (PEA; an endogenous fatty acid of ethanolamide) in DBA/2 mice, a genetic ...
AVAGLIANO, CARMEN, CALIGNANO, ANTONIO, Citraro, Rita, De Sarro, Giovambattista, Leo, Antonio, Navarra, Michele, Russo, Emilio, RUSSO, ROBERTO   +7 more
core   +1 more source

Photochemical Control of Perovskite Crystal Formation at Room Temperature

Advanced Science, EarlyView.
The authors demonstrate how ultraviolet (UV) light can enable the crystallization of two‐dimensional (2D) perovskite crystals that are otherwise difficult to grow using conventional thermal methods. These findings are supplemented with a detailed mechanistic description for the interaction of the UV irradiation with the perovskite precursor components.
Magdalena Breitwieser, Lukas E. Lehner, Julius Feigl, Lukas M. Rescher, Julia Felicitas Schwarz, Felix Mayr, Munise Cobet, Bekele Hailegnaw, Christoph Putz, Clemens Schwarzinger, Markus Clark Scharber, Markus Himmelsbach, Bert Nickel, Stepan Demchyshyn, Martin Kaltenbrunner   +14 more
wiley   +1 more source