Results 71 to 80 of about 2,924,848 (261)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Photovoltaic System For Supplying Public Lighting As Peak Demand Shaving
Eletrônica de Potência, 2007 This paper describes the design and implementation of a grid connected photovoltaic system aimed to supply energy to the public lighting during the time of high peak demand of the grid. The system is made of two main parts: the solar energy storage unit
Edilson Mineiro Sá Jr. +5 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Accounting for peak shifting in traditional cost-benefit analysis [PDF]
When cost-benefit analysis fails to account for peak-shifting the benefits of road improvement options are miscalculated. Using theory from transportation economics, we derive a simple model that disaggregates the average daily equilibrium into peak ...
Snarr, Hal W., Axelsen, Dan
core
Wind resources of southeast Australia during peak electricity demand days [PDF]
Wind Energy SciencePeaks in electricity demand are critical times when it is important to understand the contribution of wind energy to the supply of electricity. In southeast Australia, peaks in electricity demand may be caused by unusually hot or cold periods that ...
C. L. Vincent +5 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Systematic peak-load pricing, congestion premia and demand diverting: Empirical evidence [PDF]
This paper finds empirical support to systematic peak-load pricing in airlines---higher fares in ex-ante known congested periods. It estimates a congestion premia and supports the main empirical prediction in Gale and Holmes (1993)---less discount seats ...
Escobari, Diego
core
The Influence of Air-Conditioning Efficiency in the Peak Load Demand for Kuwait [PDF]
, 2007 A model co-relating the peak load demand of a utility with the allowable power rating (PR) of air-conditioning (AC) systems has been developed in this paper through a well defined methodology.
Maheshwari, G. P., Ali, A. A.
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
EnergiesBuilding energy consumption takes up over 30% of global final energy use and 26% of global energy-related emissions. In addition, building operations represent nearly 55% of global electricity consumption.
Mengchen Zhao +5 more
doaj +1 more source