Results 81 to 90 of about 2,924,848 (261)
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
This study examines the rapid growth of energy demand in Paraguay, primarily driven by intensive air conditioning use and reduced hydroelectric output due to adverse Paraná River conditions.
Derlis Salomón +3 more
doaj +1 more source
The Risk of Residential Peak Electricity Demand: A Comparison of Five European Countries
The creation of a Europe-wide electricity market combined with the increased intermittency of supply from renewable sources calls for an investigation into the risk of aggregate peak demand.
Jacopo Torriti
doaj +1 more source
What if we never run out of oil? From certainty of "peak oil" to "peak demand". [PDF]
Halttunen K, Slade R, Staffell I.
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Countercyclical Price Movements during Periods of Peak Demand: Evidence from Grocery Retail Price for Avocados [PDF]
Using a unique micro dataset and advanced panel models, this study examines the effects of demand shocks on grocery retail price for avocados, a key Californian fresh produce commodity.
Carman, Hoy F. +2 more
core
Peak Shift in Remembering [PDF]
If remembering is discriminative behaviour along the dimension of time and if, as Sargisson and White (2001) argued, generalisation around a peak can occur in this behaviour, then the peak shift which has been shown in discrimination along so many other ...
Hoan, Andros
core
Regression-SARIMA modelling of daily peak electricity demand in South Africa
In this paper, seasonal autoregressive integrated moving average (SARIMA) and regression with SARIMA errors (regression-SARIMA) models are developed to predict daily peak electricity demand in South Africa using data for the period 1996 to 2009.
Delson Chikobvu, Caston Sigauke
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source

