Results 81 to 90 of about 2,924,848 (261)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

A Framework for Assessing Peak Demand Reduction from Air Conditioning Efficiency Programs in Developing Economies: A Case Study of Paraguay

open access: yesEnergies
This study examines the rapid growth of energy demand in Paraguay, primarily driven by intensive air conditioning use and reduced hydroelectric output due to adverse Paraná River conditions.
Derlis Salomón   +3 more
doaj   +1 more source

The Risk of Residential Peak Electricity Demand: A Comparison of Five European Countries

open access: yesEnergies, 2017
The creation of a Europe-wide electricity market combined with the increased intermittency of supply from renewable sources calls for an investigation into the risk of aggregate peak demand.
Jacopo Torriti
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Countercyclical Price Movements during Periods of Peak Demand: Evidence from Grocery Retail Price for Avocados [PDF]

open access: yes
Using a unique micro dataset and advanced panel models, this study examines the effects of demand shocks on grocery retail price for avocados, a key Californian fresh produce commodity.
Carman, Hoy F.   +2 more
core  

Peak Shift in Remembering [PDF]

open access: yes, 2003
If remembering is discriminative behaviour along the dimension of time and if, as Sargisson and White (2001) argued, generalisation around a peak can occur in this behaviour, then the peak shift which has been shown in discrimination along so many other ...
Hoan, Andros
core  

Regression-SARIMA modelling of daily peak electricity demand in South Africa

open access: yesJournal of Energy in Southern Africa, 2017
In this paper, seasonal autoregressive integrated moving average (SARIMA) and regression with SARIMA errors (regression-SARIMA) models are developed to predict daily peak electricity demand in South Africa using data for the period 1996 to 2009.
Delson Chikobvu, Caston Sigauke
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

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