Results 51 to 60 of about 297,594 (318)

Adaptability of a jump movement pattern to a non-constant force field elicited via centrifugation.

PLoS ONE, 2020
Humans are accustomed to Earth's constant gravitational acceleration of 1g. Here we assessed if complex movements such as jumps can be adapted to different acceleration levels in a non-constant force field elicited through centrifugation.
Andreas Kramer, Jakob Kümmel, Maren Dreiner, Steffen Willwacher, Timo Frett, Anja Niehoff, Markus Gruber   +6 more
doaj   +1 more source

Peak Ground Acceleration Analysis using Past Earthquake Data

Journal of Physics: Conference Series, 2020
Abstract Peak Ground Acceleration (PGA) is one of the important parameters in the design of seismic resistant structures. In order to predict the value of PGA for a particular place, the past seismic history of that place in terms of data sets is required.
Swetha Elizabeth Philip, M. Helen Santhi
openaire   +2 more sources

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Estimating the upper limit of prehistoric peak ground acceleration using an in situ, intact and vulnerable stalagmite from Plavecká priepast cave (Detrekői-zsomboly), Little Carpathians, Slovakia—first results

Journal of Seismology, 2017
Earthquakes hit urban centres in Europe infrequently, but occasionally with disastrous effects. Obtaining an unbiased view of seismic hazard (and risk) is therefore very important.
K. Gribovszki, K. Kovács, P. Mónus, G. Bokelmann, P. Konečný, M. Lednická, G. Moseley, C. Spötl, R. Edwards, M. Bednarik, L. Brimich, L. Toth   +11 more
semanticscholar   +1 more source

Analisis Percepatan Tanah Maksimum dengan Menggunakan Rumusan Esteva dan Donovan (Studi Kasus pada Semenanjung Utara Pulau Sulawesi) [PDF]

, 2015
ANALISIS PERCEPATAN TANAH MAKSIMUM DENGAN MENGGUNAKAN RUMUSAN ESTEVA DAN DONOVAN (Studi Kasus Pada Semenanjung Utara Pulau Sulawesi) ABSTRAK Telah dilakukan analisis percepatan tanah maksimum di semenanjung utara Pulau Sulawesi dengan menggunakan ...
Kapojos, C. G. (Cloudya), Pasau, G. (Guntur), Tamuntuan, G. (Gerald)   +2 more
core  

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

On the correlation of seismic intensity scales with the peaks of recorded strong ground motion [PDF]

, 1975
Correlations of the recorded peak acceleration, velocity and displacement, and the Modified Mercalli intensity have been carried out for 57 earthquakes and 187 strong-motion accelerograms recorded in the Western United States.
Brady, A. G., Trifunac, M. D.
core   +1 more source

Improving the structural reliability of steel frames using posttensioned connections [PDF]

, 2019
In this paper, various moment-resisting steel frames (MRSFs) are subjected to 30 narrow-band motions scaled at different ground motion intensity levels in terms of spectral acceleration at first mode of vibration in order to perform incremental dynamic ...
Bojórquez Mora, Edén, Bojórquez Mora, Juan, Carrillo León, Julián, Formisano, Antonio, López Almansa, Francisco, López Barraza, Arturo, Reyes Salazar, Alfredo, Ruiz García, Jorge, Ruiz Gómez, Sonia Elda   +8 more
core   +2 more sources

Probabilistic seismic hazard assessment in Greece – Part 1: Engineering ground motion parameters [PDF]

Natural Hazards and Earth System Sciences, 2010
Seismic hazard assessment represents a basic tool for rational planning and designing in seismic prone areas. In the present study, a probabilistic seismic hazard assessment in terms of peak ground acceleration, peak ground velocity, Arias intensity and ...
G-A. Tselentis, L. Danciu
doaj