Results 51 to 60 of about 390,476 (288)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

A Designer’s Approach for Estimation of Nuclear-Air-Blast-Induced Ground Motion

Advances in Civil Engineering, 2018
A reliable estimate of free-field ground displacement induced by nuclear-air-blast is required for design of underground strategic structures. A generalized pseudostatic formulation is proposed to estimate nuclear-air-blast-induced ground displacement ...
Shashank Pathak, G. V. Ramana
doaj   +1 more source

Determination of Blast Vibration Safety Criteria for Buried Polyethylene Pipelines Adjacent to Blast Areas, Using Vibration Velocity and Strain Data

Sensors, 2023
In order to ensure the safe operation of buried polyethylene pipelines adjacent to blasting excavations, controlling the effects of blasting vibration loads on the pipelines is a key concern.
Shengwu Tu, Dongwang Zhong, Linna Li, Xiangchao Gong, Haohao Tao   +4 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Excitation and Abundance of C3 in star forming cores:Herschel/HIFI observations of the sight-lines to W31C and W49N [PDF]

, 2010
We present spectrally resolved observations of triatomic carbon (C3) in several ro-vibrational transitions between the vibrational ground state and the low-energy nu2 bending mode at frequencies between 1654-1897 GHz along the sight-lines to the ...
A. Coutens, A. G. G. M. Tielens, B. Godard, B. Mookerjea, Bieging, C. E. Honingh, C. Gry, C. Joblin, C. M. Persson, C. Vastel, Cernicharo, Cohen, Corbel, D. C. Lis, D. Teyssier, de Graauw, E. Dartois, E. Falgarone, E. Herbst, F. Boulanger, Falgarone, Fish, Gendriesch, Gerin, Giesen, Greaves, Gwinn, H. Gupta, Haffner, Harvey, Hassel, Herbst, Hinkle, J. Black, J. C. Pearson, J. Cernicharo, J. Krełowski, J. Martin-Pintado, J. R. Goicoechea, J. Stutzki, J. Zmuidzinas, Jensen, K. M. Menten, Keene, Lucas, M. De Luca, M. Gerin, M. Kaźmierczak, M. Perault, M. Salez, M. Schmidt, Maier, Miettinen, Mueller, Mufson, Müller, Neufeld, Nyman, Oka, P. Dieleman, P. Encrenaz, P. F. Goldsmith, P. Hennebelle, P. Hily-Blant, P. Morris, P. Roelfsema, P. Sonnentrucker, Pety, Pilbratt, Plume, R. Güsten, R. Kołos, R. Monje, R. Plume, R. Schieder, Roueff, S. Schlemmer, S. Yu, Schmuttenmaer, T. A. Bell, T. G. Phillips, T. Geballe, T. Giesen, Vastel, Ward-Thompson, Wright, Z. Makai   +86 more
core   +6 more sources

Association of Corticospinal Tract Asymmetry With Ambulatory Ability After Intracerebral Hemorrhage

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ambulatory ability after intracerebral hemorrhage (ICH) is important to patients. We tested whether asymmetry between ipsi‐ and contra‐lesional corticospinal tracts (CSTs) assessed by diffusion tensor imaging (DTI) is associated with post‐ICH ambulation.
Yasmin N. Aziz, Carl D. Langefeld, Mary E. Comeau, Miranda C. Marion, Tyler P. Behymer, Lee A. Gilkerson, Padmini Sekar, Weihong Yuan, Vivek Khandwala, Brady J. Williamson, Thomas Maloney, Achala Vagal, Pierce Boyne, Kari Dunning, Matthew L. Flaherty, Steven J. Kittner, Prachi Mehndiratta, Gunjan Y. Parikh, Michael L. James, David Roh, Fernando D. Testai, Farhaan S. Vahidy, James Thornton, Ranjit Bagga, Daniel Woo, Stacie L. Demel   +25 more
wiley   +1 more source

地震载荷下圆柱型储罐内晃荡响应的数值模拟

Dizhen xuebao
为了研究地震载荷下圆柱型储罐内液体的晃荡特性，选用15种典型的地震信号，采用计算流体力学软件Fluent进行数值仿真，以探究地震的频率、频率成分、峰值速度以及峰值加速度对晃荡波高和水动压的作用规律。结果表明：① 地震主频是影响自由液面响应的主要因素之一，当其接近储液的一阶固有频率时，会激发强烈的非线性晃荡现象，工程中应添加减晃装置；② 波高与地震峰值速度呈较强的正相关，并且低频成分的地震信号激发的波浪较其它频率成分的地震信号更为剧烈；③ 水动压在储罐上部呈对流模式分布，主要受地震主频和频率成分的影响 ...
Xin Jin, Yinjie Zou, Yusheng Wang, Chao Dai, Lü Ren, Mingming Liu, Yiyi Qin, Bin Yang   +7 more
doaj   +1 more source

Intake Ground Vortex Prediction Methods [PDF]

, 2011
For an aircraft turbofan engine in ground operations or during the take-off run a ground vortex can occur which is ingested and could potentially adversely affect the engine performance and operation.
MacManus, David G., Murphy, J. P.
core   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Performance of the P-alert real-time shakemaps system and onsite warning during the 2025 ML6.4 Dapu earthquake

Terrestrial, Atmospheric and Oceanic Sciences
On January 20, 2025, the ML6.4 Dapu earthquake struck southwestern Taiwan, causing intense shaking in Chiayi County and Tainan City. The P-Alert real-time shakemaps system generated detailed shakemaps just 36 s after the earthquake occurred. The areas of
Yih-Min Wu, Yueh-Ho Lin, Benjamin Ming Yang, Siao-Syun Ke   +3 more
doaj   +1 more source