Results 101 to 110 of about 1,720,158 (289)
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Peak hour, Sydney Harbour Bridge, 1952 [picture] /
, 1952 Title supplied by photographer.; Part of collection: Jeff Carter collection of photographs, 1952-2002.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-vn3104420.
Carter, Jeff, 1928-2010.
core
FEBS Open Bio, EarlyView.Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page +4 more
wiley +1 more source
Tradeoffs among Free-flow Speed, Capacity, Cost, and Environmental Footprint in Highway Design [PDF]
This paper investigates differentiated design standards as a source of capacity additions that are more affordable and have smaller aesthetic and environmental impacts than expressways.
Chen Feng Ng, Kenneth Small
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Aging and Cancer, EarlyView.This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Analysis of Design Rainstorm Hydrograph Based on Asymmetrical Extreme-value Copula
Renmin Zhujiang, 2020 Taking the maximum 1-hour rainfall (rain peak), maximum 6-hour rainfall and maximum 24-hour rainfall in the Caojiang River Basin from 1967 to 2013 as samples, this paper establishes the typical typhoon rainstorm hydrograph for join trainfall distribution
CHEN Zishen, ZHAO Lingling, YANG Xing
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto +12 more
wiley +1 more source
One or Two Hours of Peak Acid Output
Gastroenterology, 1980 J L, Achord, S, Wells
openaire +2 more sources