Results 41 to 50 of about 345,392 (276)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Correlation functions and emission time sequence of light charged particles from projectile-like fragment source in E/A = 44 and 77 MeV 40Ar + 27Al collisions

, 2004
Two-particle correlation functions, involving protons, deuterons, tritons, and alpha-particles, have been measured at very forward angles (0.7 deg < theta_lab < 7 deg), in order to study projectile-like fragment (PLF) emission in E/A = 44 and 77 MeV 40Ar
A. Pagano, Angélique, Avdeichikov, Boal, Bougault, C. Beck, C. Volant, D. Mahboub, Dayras, Dayras, DeYoung, DeYoung, Dorvaux, E. De Filippo, E. Pollacco, Eudes, G. Lanzanò, G. Politi, Ghetti, Ghetti, Ghetti, Ghetti, Gourio, Hagel, Helgesson, Hodgson, J. Helgesson, J.L. Charvet, Koonin, Kopylov, Kotte, Lanzanò, Lanzanò, Lanzanò, Lanzanò, Lanzanò, Larochelle, Lecolley, Lednicky, M. Geraci, Pochodzalla, Péter, Péter, R. Dayras, R. Ghetti, R. Nouicer, Rivet, S. Aiello, S. Cavallaro, Schroder, Skulski, Tilley, Tilley, Verde, Zarbakhsh   +54 more
core   +3 more sources

Delineating rockmass damage zones in blasting from in-field seismic velocity and peak particle velocity measurement

International Journal of Engineering, Science and Technology, 2011
Damage to the surrounding rock during blasting either in underground or surface excavation, is a growing concern today. It has been found that the integrity of rockmass is reduced significantly from pre to post blast condition due to disregard paid to the surrounding rockmass.
Dey, K, Murthy, VMSR
openaire   +3 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Monitoring of train-induced vibrations on rock slopes

International Journal of Distributed Sensor Networks, 2017
Train-induced vibrations will undoubtedly influence the stability of slopes near railway lines. To monitor the effects of such vibrations on slope stability, a wirelessly networked vibration test system was established, which included wirelessly ...
Jiangbo Xu, Changgen Yan, Xu Zhao, Ke Du, Heng Li, Yongli Xie   +5 more
doaj   +1 more source

Shock and Spallation Behavior of a Compositionally Complex High-Strength Low-Alloy Steel under Different Impact Stresses

Applied Sciences, 2023
The shock and spalling behavior of a compositionally complex high strength low-alloy steel (HSLA) was studied using plate impact testing. The free surface velocity of the specimen in the range of 194~938 m/s was measured by a displacement interferometer ...
Ye Lu, Junbao Li
doaj   +1 more source

Local Melting and Drag for a Particle Driven Through a Colloidal Crystal

, 2003
We numerically investigate a colloidal particle driven through a colloidal crystal as a function of temperature. When the charge of the driven particle is larger or comparable to that of the colloids comprising the crystal, a local melting can occur ...
B. N. J. Persson, C. J. Olson Reichhardt, C. Reichhardt, C. Reichhardt   +3 more
core   +1 more source

THE RELATIONSHIP BETWEEN PEAK PARTICLE VELOCITY AND VIBRATION LEVEL ON BLAST VIBRATION

Doboku Gakkai Ronbunshu, 2000
発破による振動の評価尺度として振動レベルが用いられることが多くなっているが, この場合振動波形が得られない. このため, 加速度を計測して速度に変換し, 振動の最大速度振幅と振動レベルの関係式から振動レベルを推定することが多いが, この場合, 発破方法の違いが関係式に反映されない. そこで本研究では, 重畳シミュレーションにより得られた発破振動の最大速度振幅と振動レベルを用い, 発破施工の観点から発破方法の違いによる最大速度振幅と振動レベルの関係について検討する. その結果, 初段に用いる雷管の種類, 段当り孔数, 発破パターン, 振動の継続時間が関係式のA値に及ぼす影響を明らかにした.
Takahisa SHIOTSUKI, Masahiro HASHIZUME, Kohei FURUKAWA   +2 more
openaire   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Rebound Characteristics of Wet-Shotcrete Particle Flow Jet from Wall Based on CFD-DEM

Buildings
This paper aims to reveal the motion law and collision behaviors of shotcrete particle flow jets. A physical model of the jet flow field composed of a nozzle structure and jet area was constructed and meshes with various sizes were used to mesh the ...
Lianjun Chen, Yang Zhang, Pengcheng Li, Gang Pan   +3 more
doaj   +1 more source