Results 141 to 150 of about 495,930 (304)
Applied SciencesTransmission tower guy wires are critical flexible tension members ensuring the stability and safe operation of overhead power transmission networks. However, these components are vulnerable to external impacts from falling rocks, ice masses, and other ...
Jin-Gang Yang +6 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Characterizations of long-run producer optima and the short-runapproach to long-run market equilibrium: a general theory withapplications to peak-load pricing [PDF]
This is a new formal framework for the theory of competitive equilibrium and its applications.Our "short-run approach" means the calculation of long-run producer optimaand general equilibria from the short-run solutions to the producer's profit ...
Anthony Horsley, Andrew J Wrobel
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
, 2007 A new approach to the assessment and optimization of geometric stress-concentrating features is proposed on the basis of the correspondence between sharp crack or corner stressfield intensity factors and conventional elastic stress concentration factors (
Gray, T.G.F., Wood, J.
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
, 2007 In this paper, we propose a new completely integrable hierarchy. Particularly in the hierarchy we draw two new soliton equations: 1 mt= 1 2 1/m2xxx− 1 2 1/m2 x; 2 mt+mx u2−ux 2+2m2ux=0, m=u−uxx.
Zhijun Qiao, Qiao, Zhijun
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
A Higher-Order Energy Expansion to Two-Dimensional Singularly Neumann Problems
, 2005 Of concern is the following singularly perturbed semilinear elliptic problem \begin{equation*} \left\{ \begin{array}{c} \mbox{${\epsilon}^2\Delta u -u+u^p =0$ in $\Omega$}\\ \mbox{$u>0$ in $\Omega$ and $
Yeung, W-K, Winter, M, Wei, J
core
Mixed interior and boundary peak solutions of the Neumann problem for the Henon equation in R^2
Electronic Journal of Differential Equations, 2015 Let $\Omega$ be a bounded domain in $\mathbb{R}^2$ with smooth boundary and $0\in\overline{\Omega}$, we study the Neumann problem for the Henon equation $$\displaylines{ -\Delta u+u=|x|^{2\alpha}u^p,\quad u>0 \quad \text{in } \Omega,\cr \frac ...
Yibin Zhang, Haitao Yang
doaj