Results 51 to 60 of about 4,142,971 (284)

Solutions with multiple peaks for nonlinear Kirchhoff equations on R^3

open access: yesAnnales Fennici Mathematici, 2023
In this paper, we mainly investigate the following nonlinear Kirchhoff equation \(-\left(\epsilon^2 a+\epsilon b\int_{\mathbb{R}^3}|\nabla u|^2\right)\Delta u +u =Q(x)u^{q-1}\), \(u>0\), \(x\in\mathbb{R}^{3}\), \(u\to 0\), as \(|x|\to +\infty\),   where \(a,b>0\) are constants, \(2<q<6\), and \(\epsilon>0\) is a ...
Chen, Hong, Hua, Qiaoqiao
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Effects of urea on activity and conformation of acid phosphatase from wheat germ

open access: yes浙江大学学报. 农业与生命科学版, 2004
Changes in conformation and activity of acid phosphatase from wheat germ following denaturation of the enzyme by urea solutions of different concentrations were measured by the shift in fluorescence and differential UV-absorption spectrum.
WANG Li-ming   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

The Physicomechanical Deterioration Characteristics and Mesoscopic Damage Analysis of Sandstone under Acidic Environment

open access: yesAdvances in Civil Engineering, 2020
The physicomechanical deterioration characteristics of sandstone subjected to H2SO4, HCl, and H2O solutions of different pH values are studied by the method of long-term accelerated immersion.
Runke Huo   +4 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Numerical optimization of Wells turbine for wave energy extraction

open access: yesInternational Journal of Naval Architecture and Ocean Engineering, 2017
The present work focuses multi-objective optimization of blade sweep for a Wells turbine. The blade-sweep parameters at the mid and the tip sections are selected as design variables.
Paresh Halder   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Peaked and Smooth Solitons for K*(4,1) Equation

open access: yesJournal of Applied Mathematics, 2013
This paper is contributed to explore all possible single peak solutions for the K*(4,1) equation ut=uxu2+2α(uuxxx+2uxuxx). Our procedure shows that the K*(4,1) equation either has peakon, cuspon, and smooth soliton solutions when sitting on a nonzero ...
Yongan Xie, Hualiang Fu, Shengqiang Tang
doaj   +1 more source

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