Results 51 to 60 of about 495,930 (304)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Effects of urea on activity and conformation of acid phosphatase from wheat germ
浙江大学学报. 农业与生命科学版, 2004 Changes in conformation and activity of acid phosphatase from wheat germ following denaturation of the enzyme by urea solutions of different concentrations were measured by the shift in fluorescence and differential UV-absorption spectrum.
WANG Li-ming +3 more
doaj +1 more source
Solutions with multiple peaks for nonlinear Kirchhoff equations on R^3
Annales Fennici Mathematici, 2023 In this paper, we mainly investigate the following nonlinear Kirchhoff equation \(-\left(\epsilon^2 a+\epsilon b\int_{\mathbb{R}^3}|\nabla u|^2\right)\Delta u +u =Q(x)u^{q-1}\), \(u>0\), \(x\in\mathbb{R}^{3}\), \(u\to 0\), as \(|x|\to +\infty\), where \(a,b>0\) are constants, \(2<q<6\), and \(\epsilon>0\) is a ...
Chen, Hong, Hua, Qiaoqiao
openaire +2 more sources
Spikes for the Gierer-Meinhardt system in two dimensions: The strong coupling case
, 2002 Numerical computations often show that the Gierer-Meinhardt system has stable solutions which display patterns of multiple interior peaks (often also called spots). These patterns are also frequently observed in natural biological systems.
Winter, M +3 more
core +1 more source
Advances in Civil Engineering, 2020 The physicomechanical deterioration characteristics of sandstone subjected to H2SO4, HCl, and H2O solutions of different pH values are studied by the method of long-term accelerated immersion.
Runke Huo +4 more
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Numerical optimization of Wells turbine for wave energy extraction
International Journal of Naval Architecture and Ocean Engineering, 2017 The present work focuses multi-objective optimization of blade sweep for a Wells turbine. The blade-sweep parameters at the mid and the tip sections are selected as design variables.
Paresh Halder +2 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source