Results 231 to 240 of about 176,875 (311)

Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila

Advanced Science, EarlyView.
Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu, Xuedi Zhang, Ying Zhou, Jie Zheng, Angyang Sun, Kailong Zhuang, Weiwei Bao, Guanjun Gao   +7 more
wiley   +1 more source

Willingness to pay for combined medical and old-age care services: A survey in Chengdu City, China. [PDF]

Medicine (Baltimore)
Guo CR, Lu YG, Zhu H, Zhao Y.
europepmc   +1 more source

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

Advanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen, Zixing Xu, Zerun Hao, Yanming Chen, Kai Xie, Haofan Yin, Xueying Wang, Jie Min, Sihan Sun, Baiding Chen, Chengxiu Ling, Mingming Xu, Yizhao Chen, Gang Ruan   +13 more
wiley   +1 more source

Characterisation of harmful use of alcohol in a rural setting: A Pilot study around Lake Bunyonyi in Kigezi Sub-region, Uganda

Tumwesigye NM, Mubangizi V, Karugahe W, Napyo A, Maling S, Mukose A, Gitige C, Mbuo M, Namanda C, Willcox M.   +9 more
europepmc   +1 more source

Factors associated with modern contraceptive utilization among postpartum adolescent girls and young women in rural Mara, Tanzania: facility-based cross-sectional study. [PDF]

Ther Adv Reprod Health
Sichalwe MM, Tavengana G, Behera MR, Haq FU, Egbobe JO, Ullah S, Kimaro RR, Basit A.   +7 more
europepmc   +1 more source

The Low Countries, 1000-1750 [PDF]

, 2015
Soens, Tim, Thoen, Erik
core   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source

Violence, land conflicts and the dynamics of the agrarian economy in the Brazilian Amazon. [PDF]

Cad Saude Publica
Dal'Asta AP, Farias WAA, Monteiro AMV, Monteiro AMV, Amaral S, Gontijo AB, Fernandes DA, Escada MIS.   +7 more
europepmc   +1 more source

An Increasing Misalignment Between Crop Distribution and Environmental Resources Under Climate Change in China

Advanced Science, EarlyView.
Climate change reshapes the spatial alignment between crop production and environmental resources. Using multi‐source data and a crop model, integrated climatic, water, and soil endowments for maize and wheat are quantified and compared with harvest distributions.
Zheng'e Su, Zhentao Zhang, Jin Zhao, Xia Liang, Chuang Zhao, Zhijuan Liu, Minghao Zhuang, Jing Sun, Bo Lu, Ke Liu, Johannes W. M. Pullens, Matthew T. Harrison, Deli Chen, Xiaoguang Yang   +13 more
wiley   +1 more source

Identifying factors contributing to kinesiophobia in patients post-percutaneous coronary intervention. [PDF]

BMC Nurs
Chen L, Li JY, Ren ZQ, Wang LC, Huang PY, Jiang WJ, Li C, Ding L.   +7 more
europepmc   +1 more source