Results 61 to 70 of about 2,403 (160)

Defensive medicine in dermatological practice – Dermatopathology as a mirror of structural challenges

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 3, Page 302-315, March 2026.
Summary Defensive medicine refers to diagnostic or therapeutic actions taken primarily to reduce legal liability rather than to benefit the patient. In dermatopathology, defensive practices manifest in frequent immunohistochemical testing, overly cautious report phrasing, and reliance on multidisciplinary tumor boards.
Cornelia Sigrid Lissi Müller, Torsten Hansen, Claus Renzelmann   +2 more
wiley   +1 more source

Case 1 − A case of gynecological PEComa

, 2017
Perivascular epithelioid cell tumors (PEComas) are a heterogeneous group of rare mesenchymal neoplasms composed of epithelioid cells which express melanocytic and myogenic markers, such as HMB-45, desmin and actin.
Caterina Fontanella, Maria Luisa Carcangiu, Domenica Lorusso, Bruno Vincenti   +3 more
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, Volume 20, Issue 2, Page 493-510, February 2026.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Perivascular epithelioid cell tumor (PEComa) of the kidney: an overview of its management and outcomes

Journal of International Medical Research, 2020
Perivascular epithelioid cell tumor (PEComa) is a rare mesenchymal tumor with unique histological and immunohistochemical characteristics. Malignant renal cell carcinoma is even rarer and its biological behavior is still not clear.
Yu Yang, Xiaohong Yu, Bo Lu, Zhiqiang Shao   +3 more
doaj   +1 more source

Melanotic PEComa

International audiencePerivascular epithelioid cell neoplasms (PEComas) are tumors of uncertain cell lineage that show a strong female predominance. Their hallmark is the presence of combined smooth muscle and melanocytic differentiation.
Papke, David, Hanna, John, Pissaloux, Daniel, Tirode, Franck, Fletcher, Christopher D.M., de la Fouchardiere, Arnaud, Russell-Goldman, Eleanor   +6 more
core   +1 more source

Youngest known case of a pancreatic perivascular epithelioid cell tumor

JPGN Reports, Volume 7, Issue 1, Page 137-141, February 2026.
Abstract Perivascular epithelioid cell tumors (PEComas) are a rare type of mesenchymal tumor that can arise in any part of the body. As of 2024, 37 cases of pancreatic PEComas had been reported in the literature with patients ranging in age from 17 to 74 years old.
Laura Gilligan, Wesley C. Judy, Bryan Clary, Timothy Fairbanks, Denise Malicki, Tom K. Lin   +5 more
wiley   +1 more source

Genomic Profiling of Pediatric Solid Tumors With a Dual DNA/RNA Panel: JCCG‐TOP2 Study

Cancer Science, Volume 117, Issue 2, Page 522-535, February 2026.
In the JCCG‐TOP2 nationwide pediatric cancer genomic profiling study, 204 patients' tumors and peripheral blood from 50 institutions across Japan were successfully analyzed using a dual DNA/RNA panel. A total of 147 (72%) had potentially actionable findings, including diagnostic, prognostic, and therapeutic findings in 111 (54%), 61 (30%), and 64 (31%),
Kayoko Tao, Takako Yoshioka, Miho Kato, Kazuyuki Komatsu, Shinichi Tsujimoto, Kenichi Sakamoto, Kazuki Tanimura, Minako Sugiyama, Masahiro Sekiguchi, Yoshiko Nakano, Yoshihiro Otani, Yasushi Yatabe, Akihiko Yoshida, Hajime Okita, Junko Hirato, Kenichi Kohashi, Yukichi Tanaka, Shinji Kohsaka, Takashi Kubo, Kuniko Sunami, Makoto Hirata, Shuichi Tsutsumi, Hiroyuki Aburatani, Katsuyoshi Koh, Masahiro Hirayama, Shuhei Karakawa, Yukayo Terashita, Hiroyuki Fujisaki, Takeshi Yagi, Akihiro Yoneda, Shinji Mochizuki, Hiroyuki Shichino, Tatsuya Suzuki, Tetsuya Takimoto, Koichi Ichimura, Chitose Ogawa, Kimikazu Matsumoto, Hitoshi Ichikawa, Motohiro Kato   +38 more
wiley   +1 more source

A perivascular epithelioid cell neoplasm of the bladder diagnosed after six years: A case report

Urology Case Reports
Perivascular epithelioid cell neoplasm (PEComa) is a rare mesenchymal-derived tumor with specific histological and immunohistochemical manifestations. Given the rarity of bladder PEComa, standardized diagnostic and therapeutic protocols have yet to be ...
Ji-yao Yang, Xiao-rong Yang, Wei-xiang Hei, Yi-dao Liu   +3 more
doaj   +1 more source

Perivascular epithelioid cell tumor (PEComa) of the ascending colon: the implication of IFN-α2b treatment [PDF]

Korean Journal of Pediatrics, 2010
A 7-year-old boy presented with hematochezia and abdominal pain. A 3.7-cm-sized mass was identified in the ascending colon by abdominal computed tomography and colonoscopy. The patient underwent surgical resection. Pathological examination revealed a low-
Sun Ju Park, Dong Kyun Han, Hee Jo Baek, Sang Young Chung, Jong Hee Nam, Hoon Kook, Tai Ju Hwang   +6 more
doaj   +1 more source

Primary perivascular epithelioid cell tumor of the liver not related to hepatic ligaments: hepatic PEComa as an emerging entity [PDF]

, 2008
Primary perivascular epithelioid cell tumor (PEComa) of the liver is a very rare example of an emerging family of hepatic PEC tumors. Only few cases have been described so far.
Candinas, Daniel, Berger, B, Kappeler, Andreas, von der Brelie, Christian, Berger, Barbara, von der Brelie, C, Zimmermann, A, Zimmermann, Arthur, Candinas, D, Kappeler, A   +9 more
core