Results 51 to 60 of about 2,167 (210)

A Structural Basis for Regulation of Actin Polymerization by Pectenotoxins [PDF]

open access: yesJournal of Molecular Biology, 2007
(PTXs) are polyether macrolides found in certain dinoflagellates, sponges and shellfish, and have been associated with diarrhetic shellfish poisoning. In addition to their in vivo toxicity, some PTXs are potently cytotoxic in human cancer cell lines.
John S, Allingham   +2 more
openaire   +2 more sources

Function-Oriented Studies Targeting Pectenotoxin 2: Synthesis of the GH-Ring System and a Structurally Simplified Macrolactone

open access: yesOrganic Letters, 2017
A chemical foundation for function-oriented studies of pectenotoxin 2 (PTX2) is described. A synthesis of the bicyclic GH-system, and the design and synthesis of a PTX2-analogue, is presented.
Natasha F. O’Rourke   +4 more
semanticscholar   +1 more source

Marine Biotoxins in Whole and Processed Scallops from the Argentine Sea

open access: yesMarine Drugs, 2022
Harmful algal blooms are an increasing worldwide threat to the seafood industry and human health as a consequence of the natural production of biotoxins that can accumulate in shellfish.
Alejandra B. Goya   +8 more
doaj   +1 more source

A THEORETICAL ESTIMATION OF EXPOSURE TO SHELLFISH TOXINS OF DIFFERENT POPULATION GROUPS IN BULGARIA

open access: yesArchives of the Balkan Medical Union, 2021
Introduction. Shellfish poisoning could be caused by ingestion of shellfish contaminated by bacteria, viruses, heavy metals, pesticides, marine biotoxins etc. The objective of the study was to determine the theoretical human exposure to shellfish toxins
Zlatina V. PETEVA   +4 more
doaj   +1 more source

Novel synthetic routes towards trans-THFs and application towards the FG fragment of pectenotoxin-4 [PDF]

open access: yes, 2013
trans-2,5-Disubstituted tetrahydrofurans (THFs) are a common structural motif in a multitude of biologically active natural products. This thesis explores new synthetic routes for their synthesis and subsequent application towards the C31-40 fragment of ...
Tucker, Michael J, Donohoe, Timothy J
core   +2 more sources

LC-MS/MS method for the detection of multiple classes of shellfish toxins

open access: yesCzech Journal of Food Sciences, 2019
Marine shellfish toxins are seafood safety problems of global concern. Herein the analysis of six shellfish toxins, regulated by European Union, with one single run by LC-MS/MS with acidic mobile phase was developed.
Ling Jan Chiou   +2 more
doaj   +1 more source

Current situation on analysis of marine toxins

open access: yesReviews in Analytical Chemistry, 2013
Marine toxins are a food safety concern worldwide. This review discusses current analytical methods for those toxins that are legally regulated in Europe, namely domoic acid, saxitoxin, okadaic acid, yessotoxin, pectenotoxin and azaspiracids, and all ...
Botana Ana M.   +4 more
doaj   +1 more source

Report on the First Detection of Pectenotoxin-2, Spirolide-A and Their Derivatives in French Shellfish

open access: yesMarine Drugs, 2007
In the context of the French Phytoplankton and Phycotoxins MonitoringNetwork (REPHY) programme, shellfish samples were harvested from different locationswhere harmful algae blooms were known to have occurred.
Eric Abadie   +4 more
doaj   +1 more source

Lipophilic Toxin Profile in Mytilus galloprovincialis during Episodes of Diarrhetic Shellfish Poisoning (DSP) in the N.E. Adriatic Sea in 2006

open access: yesMolecules, 2011
Dinophysis spp. blooms and related shellfish toxicity events of diarrhetic shellfish poisoning (DSP) have been the most reported toxicity event through the Croatian National monitoring program.
Sanda Skejic   +7 more
doaj   +1 more source

A Screening Tool for the Direct Analysis of Marine and Freshwater Phycotoxins in Organic SPATT Extracts from the Chesapeake Bay

open access: yesToxins, 2020
Many detection methods for phycotoxins, bioactive compounds produced by harmful algae, focus on one compound or a class of related compounds. Multiple harmful algal species often co-occur in the environment, however, emphasizing the need to analyze for ...
Michelle D. Onofrio   +3 more
doaj   +1 more source

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