Results 81 to 90 of about 173,289,968 (231)

Ethical Receptions

open access: yes, 2020
The flyer set (1 HEX) was developed in preparation for a 3-way lecture with Dániel Péter Biró, Bojana Cvejic and Theodor Barth. Title: Receptions of Spinoza. Text: Ethica. Reading (music): Nulla Res Singularis.
Barth, Theodor
core   +1 more source

Computationally Evidence‐Grounded Sequence‐First Design of Peptide Binders

open access: yesAdvanced Science, EarlyView.
BOND‐PEP enables controllable, sequence‐first peptide binder design by grounding generation in binding evidence retrieved for each target. It uses topology‐conditioned message passing to integrate relevant peptide examples with the target protein sequence, forming a residue‐level representation that guides the generation of diverse, target‐specific ...
Wenze Ding
wiley   +1 more source

Shaking students' cages: A Freirean pedagogy that challenged PETE students' beliefs about physical education

open access: yes, 2016
This paper reports on the findings of a study that explored the influence of a four-year physical education teacher education (PETE) programme on the beliefs about physical education of the graduating students.
Philpot, RA
core  

A Site‐Aware Representation Learning Framework For Unified Molecular Interaction Modeling and Generative Design

open access: yesAdvanced Science, EarlyView.
MolDBG is a site‐aware, sequence‐only framework that unifies drug‐target affinity prediction, binding‐site identification, and affinity‐conditioned molecular generation for structured proteins. Guided by multi‐task binding‐site supervision, it aligns interaction‐critical residues before learning drug‐target representations and simultaneously infers ...
Gang Luo   +6 more
wiley   +1 more source

Critical Digital Pedagogy Faculty Mentoring Network: Midterm Report

open access: yes, 2017
This report details the mid-term status of the Critical Digital Pedagogy Faculty Mentoring Network project funded through the University of North Texas Office of Faculty Success Team Mentoring ...
Keralis, Spencer D. C.
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Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo

open access: yesAdvanced Science, EarlyView.
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao   +12 more
wiley   +1 more source

Uhrf1‐Mediated PKM2 Degradation via Ubiquitination Alleviates Inflammation and Pyroptosis in Inflammatory Bowel Disease

open access: yesAdvanced Science, EarlyView.
Uhrf1‐mediated PKM2 ubiquitination and degradation repressed the nuclear translocation of PKM2, and EPT served as a molecular glue capable of targeting the Uhrf1–PKM2 complex to alleviate the IBD course, suggesting that the Uhrf1–PKM2 axis was a previously unrecognized strategy for treating IBD.
Juan Zhang   +9 more
wiley   +1 more source

VOLUME 4, ISSUE 1 — INTERSECTIONS: BELIEF, PEDAGOGY, AND POLITICS

open access: yes, 2017
We are pleased to present issue 4.1 of Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy, in which we explore belief systems, pedagogy, and politics.

core  

The Adipose‐Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte‐Derived Neurotrophic Factor for WAT Browning

open access: yesAdvanced Science, EarlyView.
As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia   +13 more
wiley   +1 more source

Preview Receptions

open access: yes
Photograph used for a newspaper owned by the Oklahoma Publishing Company. Caption: "Preview Receptions, parties for members of the association, call for late day dresses of the type worn by Mrs. Todd Archibald, left above, and Mrs. Charles Covington.

core  

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