Results 81 to 90 of about 13,973,138 (276)

Edge-localized mode avoidance and pedestal structure in I-mode plasmas

open access: yes, 2014
I-mode is a high-performance tokamak regime characterized by the formation of a temperature pedestal and enhanced energy confinement, without an accompanying density pedestal or drop in particle and impurity transport.
J. Walk   +14 more
semanticscholar   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Pedestal structure and stability at low collisionality in TCV

open access: yes, 2022
ITER will operate at low pedestal collisionality (?*eeped) and high separatrix density (n esep).
Frassinetti L   +7 more
openaire   +4 more sources

Analysis of proportional conception of the historical truss Church of St. Martin in Dolní Újezd

open access: yesMATEC Web of Conferences, 2017
The late-Romanesque St. Martin’s Church in Dolní Újezd was probably built in the mid-13th century. The nave has a wooden joist ceiling whose beams serve as tie beams too. The Gothic vaults above the presbytery date from ’30s of the 15th century.
Krušinský Peter   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Efficient ion beam generation in laser interactions with micro-structured targets

open access: yesEPJ Web of Conferences, 2013
The maximum ion energy and acceleration efficiency have to be increased for practical applications of intense ion beams produced by intense short laser pulses incident on a thin foil.
Limpouch J.   +8 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

TEMUAN STRUKTUR DI SITUS AIMOLI KABUPATEN ALOR, NUSA TENGGARA TIMUR

open access: yesForum Arkeologi, 2017
The finding of structure in Aimoli, Alor is archaeologically important. This research aims to determine the form, function, role, and the cause of the structure damage. Methods that applied are excavation, survey, and interview.
I Wayan Suantika
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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