Results 91 to 100 of about 6,875,269 (237)

Spatiotemporal structure of edge harmonic oscillation and its role in ELM-free QH-mode at KSTAR

Nuclear Fusion
In Quiescent H-mode (QH-mode), edge-localized modes (ELMs) are naturally replaced by a low- $n$ edge harmonic oscillation (EHO), yet the self-regulating transport mechanism driven by the EHO remains insufficiently understood.
Jaehyun Lee, SangKyeun Kim, Young-Mu Jeon, Minwoo Kim, Dong-Kwon Kim, Gunsu S. Yun   +5 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Identification of a window for quiescent H-mode operation in MHD stability diagram of DIII-D plasmas

Nuclear Fusion
A window for quiescent H-mode (QH-mode) operation in DIII-D plasmas in the diagram of pedestal magnetohydrodynamic (MHD) stability was identified through linear MHD stability analysis, accounting for the effects of plasma rotation and ion diamagnetic ...
N. Aiba, X. Chen, T.H. Osborne, K.H. Burrell   +3 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Tokamak edge-SOL turbulence in H-mode conditions simulated with a global, electromagnetic, transcollisional drift-fluid model

Nuclear Fusion
The design of commercially feasible magnetic confinement fusion reactors strongly relies on the reduced turbulent transport in the plasma edge during operation in the high confinement mode (H-mode).
Wladimir Zholobenko, Kaiyu Zhang, Andreas Stegmeir, Jan Pfennig, Konrad Eder, Christoph Pitzal, Philipp Ulbl, Michael Griener, Lidija Radovanovic, Ulrike Plank, the ASDEX Upgrade Team   +10 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Golden oak pedestal table

, 2005
Support furnitureWalnut pedestal table with golden oak stained finish, round top with plain frieze, on plain turned pedestal with four shaped feet. Part of a five-piece set consisting of a table and four chairs. Signed.walnut2 1/2"h x 4"
Carlisle, Robert L.
core