Results 111 to 120 of about 69,287 (288)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Analysis of proportional conception of the historical truss Church of St. Martin in Dolní Újezd

open access: yesMATEC Web of Conferences, 2017
The late-Romanesque St. Martin’s Church in Dolní Újezd was probably built in the mid-13th century. The nave has a wooden joist ceiling whose beams serve as tie beams too. The Gothic vaults above the presbytery date from ’30s of the 15th century.
Krušinský Peter   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Efficient ion beam generation in laser interactions with micro-structured targets

open access: yesEPJ Web of Conferences, 2013
The maximum ion energy and acceleration efficiency have to be increased for practical applications of intense ion beams produced by intense short laser pulses incident on a thin foil.
Limpouch J.   +8 more
doaj   +1 more source

Scintillation counter with MRS APD light readout

open access: yes, 2006
START, a high-efficiency and low-noise scintillation detector for ionizing particles, was developed for the purpose of creating a high-granular system for triggering cosmic muons.
A. Akindinov   +13 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

TEMUAN STRUKTUR DI SITUS AIMOLI KABUPATEN ALOR, NUSA TENGGARA TIMUR

open access: yesForum Arkeologi, 2017
The finding of structure in Aimoli, Alor is archaeologically important. This research aims to determine the form, function, role, and the cause of the structure damage. Methods that applied are excavation, survey, and interview.
I Wayan Suantika
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

High granularity tracker based on a Triple-GEM optically read by a CMOS-based camera

open access: yes, 2015
The detection of photons produced during the avalanche development in gas chambers has been the subject of detailed studies in the past. The great progresses achieved in last years in the performance of micro-pattern gas detectors on one side and of ...
Marafini, Michela   +5 more
core   +1 more source

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