Results 201 to 210 of about 6,542,588 (257)
Rheumatology &Autoimmunity, EarlyView.A proposed mechanistic framework of systemic lupus erythematosus (SLE) and autoimmune thyroid disease (AITD) pathogenesis. In Stage 1, genetically susceptible individuals harbor risk variants within major histocompatibility complex (HLA) and non‐HLA loci that impair central and peripheral immune tolerance mechanisms within the thymic and peripheral ...
Elisa Elisa +3 more
wiley +1 more source
Microbiota as the candidate biomarker in pediatric obstructive sleep apnea
Sleep Research, EarlyView.Abstract Pediatric obstructive sleep apnea (OSA) is a form of sleep‐disordered breathing in children. Recent studies have focused on characterizing microbiota alterations associated with pediatric OSA and identifying microbial features that may have potential value as future biomarkers. The most commonly used approach for microbiota profiling is second‐
Xiaoyan Li +4 more
wiley +1 more source
The 5T Paradox of Triclosan: From Toiletries to Toxic Trash, a Growing Threat to Humanity
Environmental Toxicology, EarlyView.ABSTRACT Triclosan (TCS) persists as a contaminant of concern in the Anthropocene, despite regulatory actions. Environmental dissemination continues through wastewater effluents, biosolid application, and improper disposal practices. This narrative review synthesizes current evidence regarding triclosan's environmental fate, transformation pathways ...
Temitope Aribigbola +10 more
wiley +1 more source
Technology Assisted Intraoperative Anatomic Visualization: Surgeon Perspectives and Unmet Needs
World Journal of Surgery, EarlyView.Iatrogenic injury to critical anatomic structures remains a leading source of surgical morbidity, most commonly due to visual misperception rather than technical error. Despite a rapidly expanding ecosystem of intraoperative visualization adjuncts, the surgeon's perspective on current limitations and unmet needs has not been evaluated. The objective of
Yann Sakref +9 more
wiley +1 more source
US Life Expectancy and Increasing Mortality Rates: An Analysis of the Crisis
The Milbank Quarterly, EarlyView.Policy Points US life expectancy is shorter than in other high‐income countries and the gap has widened dramatically over time, driven in particular by rising mortality rates that threaten the probability that youth can survive to middle age, or even adulthood.
STEVEN H. WOOLF
wiley +1 more source
Child Health Challenges, Ecosystem Mismatches, and the Case for State‐Level Policy Innovation
The Milbank Quarterly, EarlyView.Policy Points From 2011‐2023, US children's health deteriorated across >170 indicators. Chronic conditions rose from 25.8% to 31%, risk of anxiety tripled, and autism and learning disability more than doubled. Policies based on biomedical models have failed to address these trends.
NEAL HALFON, SHIRLEY RUSS
wiley +1 more source
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Background Pelvic organ prolapse (POP) affects up to 50% of postmenopausal women, negatively impacting sexual function and quality of life. While surgery remains the primary treatment, increasing attention has been given to perioperative vaginal oestrogen therapy and its potential impact on surgical outcomes.
Gilda Sicilia +7 more
wiley +1 more source
Surgical Management of Non‐Allergic Rhinitis—An EAACI Task Force Position Paper
Allergy, EarlyView.ABSTRACT Non‐allergic rhinitis is a frequent yet underdiagnosed cause of chronic nasal symptoms, including nasal congestion, rhinorrhoea, and upper airway hyperreactivity. Its pathophysiology involves neurogenic dysregulation, leading to excessive mucus production and vasodilation.
Marie Lundberg +18 more
wiley +1 more source