Results 81 to 90 of about 1,413,284 (292)

Dynamic vascular changes in chronic thromboembolic pulmonary hypertension after pulmonary endarterectomy [PDF]

, 2020
Residual pulmonary hypertension is an important sequela after pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension. Recurrent thrombosis or embolism could be a contributor to this residual pulmonary hypertension but the potential ...
Symersky, Petr, Braams, N.J., Bogaard, Harm Jan, Lely, R.J., Boonstra, Anco, Lely, Rutger J., Klok, Frederikus A., Lilian J. Meijboom, Frederikus A. Klok, Braams, Natalia J., Bogaard, Harm-Jan, Bonta, P.I., Nossent, E.J., Vonk Noordegraaf, Anton, Nossent, Esther J., Ruigrok, Dieuwertje, Meijboom, Lilian J., Natalia J. Braams, Meijboom, L.J., Dieuwertje Ruigrok, Anton Vonk Noordegraaf, Harm‐Jan Bogaard, Esther J. Nossent, Symersky, P., Anco Boonstra, Peter I. Bonta, Bogaard, H.J., Ruigrok, D., Noordegraaf, A.V., Bonta, Peter I., Boonstra, A., Klok, F.A., Rutger J. Lely, Petr Symersky   +33 more
core   +1 more source

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

Arthritis &Rheumatology, EarlyView.
Objective TypeI interferonopathies are heterogeneous diseases driven by dysregulated type I interferon (IFN‐I) signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. The aim of this study was to characterize the clinical, immunologic, genetic, molecular profiles of patients with suspected ...
Ismail Yaz, Seza Ozen, Hacer Neslihan Bildik, Canberk Ipsir, Dilara Unal, Saliha Esenboga, Begum Cicek, Mehmet Emin Seker, Fatima Aerts‐Kaya, Seher Sener, Mehmet Orhan Erkan, Hanife Avci, Deniz Cagdas, Ilhan Tezcan   +13 more
wiley   +1 more source

Pulmonary thromboendarterectomy in pediatric patients: Report of three cases

The Turkish Journal of Pediatrics, 2018
Chronic thromboembolic pulmonary hypertension (CTEPH), which occurs due to impartial resolution of the pulmonary thrombus, is a rare type of pulmonary hypertension.
Ulaş Kumbasar, Ebru Aypar, Tevfik Karagöz, Metin Demircin, Rıza Doğan   +4 more
doaj   +1 more source

Diagnostic tools in pulmonary arterial hypertension management

, 2010
An accurate differential diagnosis is crucial in pulmonary hypertension/pulmonary arterial hypertension (PH/PAH), because the treatment options in the different PH/PAH groups and subgroups differ substantially.
Vonk Noordegraaf, Anton, Heinrike Wilkens, Vonk-Noordegraaf, Anton, Wilkens, Heinrike, Anton Vonk Noordegraaf, Robert Naeije, Naeije, Robert   +6 more
core   +1 more source

Expert Perspective: Toward Treat‐to‐Target Management in Adult Idiopathic Inflammatory Myopathies

Arthritis &Rheumatology, Accepted Article.
Treat‐to‐target (T2T) has transformed the management of several rheumatic diseases through predefined therapeutic goals, structured disease assessment, and timely treatment adjustment. Despite major advances in the understanding and treatment of idiopathic inflammatory myopathies (IIM), a formal T2T framework for adult IIM has not yet been established.
Shiri Keret, Nantakarn Pongtarakulpanit, Rohit Aggarwal   +2 more
wiley   +1 more source

Metabolism of asymmetric dimethylarginines is regulated in the lung developmentally and with pulmonary hypertension induced by hypobaric hypoxia [PDF]

, 2003
Background— Nitric oxide (NO) plays an important part in lowering pulmonary vascular resistance after birth, and in persistent pulmonary hypertension of the newborn (PPHN), NO-mediated dilation is dysfunctional.
Vallance, Patrick, Leiper, James M., Haworth, SG, Leiper, JM, Arrigoni, FI, Arrigoni, Francesca I., Vallance, P, Haworth, Sheila G.   +7 more
core   +1 more source

Pentoxifylline dose finding trial in preterm neonates with suspected late onset sepsis (PTX‐trial)

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study (PTX‐trial) is to determine the optimal dose of pentoxifylline (PTX) in preterm neonates (gestational age < 30 weeks) with (suspected) late onset sepsis (LONS). Methods The PTX‐trial is a prospective multicentre open‐label sequential dose‐optimization study with an adapted continual reassessment method.
Serife Kurul, H. Rob Taal, Jan Mazela, Ryszard Lauterbach, Irwin K. M. Reiss, Karel Allegaert, Robert B. Flint, Sinno H. P. Simons   +7 more
wiley   +1 more source

Chronic Thromboembolic Pulmonary Hypertension in a Child With Sickle Cell Disease

Frontiers in Pediatrics, 2020
Chronic thromboembolic pulmonary hypertension is a potentially curable form of pre-capillary pulmonary hypertension (PH) resulting from incomplete resolution of pulmonary thromboemboli.
Robert Spencer, Gerson Valencia Villeda, Koji Takeda, Erika B. Rosenzweig   +3 more
doaj   +1 more source

Sildenafil in pediatric pulmonary arterial hypertension

Journal of Postgraduate Medicine, 2015
Pulmonary arterial hypertension (PAH) is a life-threatening disease of varied etiologies. Although PAH has no curative treatment, a greater understanding of pathophysiology, technological advances resulting in early diagnosis, and the availability of several newer drugs have improved the outlook for patients with PAH ...
Dhariwal, AK, Bavdekar, SB
openaire   +2 more sources

The Pathobiology of Chronic Thromboembolic Pulmonary Hypertension

, 2016
Chronic thromboembolic pulmonary hypertension (CTEPH) is a late sequel of venous thromboembolism that cannot be completely reproduced in animal models. The prevalence of CTEPH in humans is estimated at roughly 17-20 per million; however, partly because ...
Vonk Noordegraaf, Anton, Peter Dorfmüller, Dorfmüller, Peter, Irene M. Lang, Anton Vonk Noordegraaf, Lang, Irene M   +5 more
core   +1 more source