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Management of Pediatric Tumors With Vascular Extension [PDF]

open access: yesFrontiers in Pediatrics, 2022
Background: Pediatric tumors can present with vascular extension to the inferior vena cava and right atrium, which impacts the surgical strategy and can be challenging during surgical treatment.
Mayara Caroline Amorim Fanelli   +10 more
doaj   +2 more sources

Non-cancer effects after proton beam therapy for pediatric tumors- a narrative review [PDF]

open access: yesFrontiers in Oncology
IntroductionRadiation therapy can cause serious complications and side effects, especially in children. Proton beam therapy is considered as safer and more effective than traditional photon therapy because this type of modality offers precise radiation ...
Anna Zając-Grabiec   +5 more
doaj   +2 more sources

Pediatric Spinal Tumors

open access: yesPediatric Neurology Briefs, 2001
The clinical outcome and surgical treatment of 34 pediatric spinal tumors seen over an 18-year period (1981-1999) were analysed in a retrospective study at the Neurosurgical University Hospital of Frankfurt am Main, Germany.
J Gordon Millichap
doaj   +3 more sources

Pediatric brain tumors

open access: yesNepal Journal of Neuroscience, 2003
Tumors of the central nervous system are, as a group, the most common solid tumor of childhood. Despite significant advances in the diagnosis and treatment of pediatric malignancies elsewhere in the body, tumor of the brain continue to affect ...
Kevin L. Stevenson, MD
doaj   +3 more sources

Incidence and risk factors for stroke after hip fracture: a meta-analysis

open access: yesScientific Reports, 2023
Hip fractures represent a high burden and are associated with mortality in up to 30% of the cases. Stroke complications can be devastating and increase mortality and disability in elderly patients.
José María Lamo-Espinosa   +3 more
doaj   +1 more source

VRK3 depletion induces cell cycle arrest and metabolic reprogramming of pontine diffuse midline glioma - H3K27 altered cells

open access: yesFrontiers in Oncology, 2023
We previously identified VRK3 as a specific vulnerability in DMG-H3K27M cells in a synthetic lethality screen targeting the whole kinome. The aim of the present study was to elucidate the mechanisms by which VRK3 depletion impact DMG-H3K27M cell fitness.
Virginie Menez   +18 more
doaj   +1 more source

RETRACTED ARTICLE: Efficacy and safety of arthroscopy in femoroacetabular impingement syndrome: a systematic review and meta-analysis of randomized clinical trials

open access: yesScientific Reports, 2023
This study aimed to compare the efficacy and safety of arthroscopy with physiotherapy or joint lavage in patients with femoroacetabular impingement (FAI).
José María Lamo-Espinosa   +3 more
doaj   +1 more source

Integrating scRNA and bulk-RNA sequencing develops a cell senescence signature for analyzing tumor heterogeneity in clear cell renal cell carcinoma

open access: yesFrontiers in Immunology, 2023
IntroductionCellular senescence (CS) plays a critical role in cancer development, including clear cell renal cell carcinoma (ccRCC). Traditional RNA sequencing cannot detect precise molecular composition changes within tumors. This study aimed to analyze
Qiming Gong   +5 more
doaj   +1 more source

Pediatric genitourinary tumors [PDF]

open access: yesCurrent Opinion in Oncology, 2009
We will review the 2007/2008 literature on pediatric genitourinary tumors.Newly identified constitutional epigenetic defects in Wilms tumor genes extend the understanding of Wilms tumor risk in children lacking syndromic features, and add to the complexity of the pathogenesis of these tumor suppressor genes.
Sharon M, Castellino   +2 more
openaire   +2 more sources

Technical Validation and Clinical Utility of an NGS Targeted Panel to Improve Molecular Characterization of Pediatric Acute Leukemia

open access: yesFrontiers in Molecular Biosciences, 2022
Development of next-generation sequencing (NGS) has provided useful genetic information to redefine diagnostic, prognostic, and therapeutic strategies for the management of acute leukemia (AL).
Clara Vicente-Garcés   +23 more
doaj   +1 more source

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