Results 41 to 50 of about 83,831 (259)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Reproductive success of captively bred and naturally spawned Chinook salmon colonizing newly accessible habitat

open access: yesEvolutionary Applications, 2013
Captively reared animals can provide an immediate demographic boost in reintroduction programs, but may also reduce the fitness of colonizing populations.
Joseph H. Anderson   +3 more
doaj   +1 more source

Hereditary Gingival Fibromatosis: Report of Family Pedigree of Three Generations [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2019
Gingival enlargement or gingival overgrowth can be defined as increase in the size of gingiva, caused due to a variety of etiological factors. One of the causes of gingival enlargement is hereditary gingival fibromatosis, which is a genetic disorder ...
JAIDEEP MAHENDRA   +3 more
doaj   +1 more source

Pedigree and Pedigree Import Wizard

open access: yesHortScience, 1998
Pedigree for Windows is a user-friendly program that allows the user to trace agronomic characteristics, draw pedigrees, and view images of several fruit crops, including more than 1400 apple, 800 strawberry, 800 almond, 100 blackberry, 80 blueberry, 790 pear, 200 raspberry examples.
openaire   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Association between family history, mutation locations, and prevalence of BRCA1 or 2 mutations in ovarian cancer patients

open access: yesCancer Medicine, 2019
We investigated the prevalence of germline BRCA mutations in a population‐based cohort of Austrian women diagnosed with ovarian cancer and its association with family history of cancer.
Christian F. Singer   +9 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Supporting long‐term sustainability of ex situ collections using a pedigree‐based population management approach

open access: yesApplications in Plant Sciences, 2022
Premise Living collections maintained for generations are at risk of diversity loss, inbreeding, and adaptation to cultivation. To address these concerns, the zoo community uses pedigrees to track individuals and implement crosses that maximize founder ...
Jeremy A. Foster   +4 more
doaj   +1 more source

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