Results 61 to 70 of about 223,945 (287)
Fast Genome-Wide QTL Association Mapping on Pedigree and Population Data [PDF]
, 2014 Since most analysis software for genome-wide association studies (GWAS) currently exploit only unrelated individuals, there is a need for efficient applications that can handle general pedigree data or mixtures of both population and pedigree data.
Blangero, John +5 more
core +1 more source
Removing exogenous information using pedigree data
, 2011 Management of certain populations requires the preservation of its pure genetic background. When, for different reasons, undesired alleles are introduced, the original genetic conformation must be recovered.
A Caballero +31 more
core +2 more sources
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Evolutionary Applications, 2013 Captively reared animals can provide an immediate demographic boost in reintroduction programs, but may also reduce the fitness of colonizing populations.
Joseph H. Anderson +3 more
doaj +1 more source
Hereditary Gingival Fibromatosis: Report of Family Pedigree of Three Generations [PDF]
Journal of Clinical and Diagnostic Research, 2019 Gingival enlargement or gingival overgrowth can be defined as increase in the size of gingiva, caused due to a variety of etiological factors. One of the causes of gingival enlargement is hereditary gingival fibromatosis, which is a genetic disorder ...
JAIDEEP MAHENDRA +3 more
doaj +1 more source
The Consequences of Polyandry for Sibship Structures, Distributions of Relationships and Relatedness, and Potential for Inbreeding in a Wild Population [PDF]
, 2017 We thank the Tsawout and Tseycum First Nations for access to Mandarte Island, Pirmin Nietlisbach, Lukas Keller, Greta Bocedi, Brad Duthie, and Matthew Wolak for helpful discussions, and the European Research Council, National Sciences and Engineering ...
Arcese, Peter +2 more
core +2 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Comparison of alternative approaches to single-trait genomic prediction using genotyped and non-genotyped Hanwoo beef cattle. [PDF]
, 2017 BackgroundGenomic predictions from BayesA and BayesB use training data that include animals with both phenotypes and genotypes. Single-step methodologies allow additional information from non-genotyped relatives to be included in the analysis. The single-
Cheng, Hao +7 more
core +3 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The largest strongly connected component in Wakeley et al's cyclical pedigree model [PDF]
, 2014 We establish a link between Wakeley et al's (2012) cyclical pedigree model from population genetics and a randomized directed configuration model (DCM) considered by Cooper and Frieze (2004).
Blath, Jochen +2 more
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