Results 71 to 80 of about 195,365 (311)

Understanding Surface Adhesion in Nature: A Peeling Model

open access: yesAdvancement of science, 2016
Nature often exhibits various interesting and unique adhesive surfaces. The attempt to understand the natural adhesion phenomena can continuously guide the design of artificial adhesive surfaces by proposing simplified models of surface adhesion.
Zhen Gu   +3 more
semanticscholar   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Low-Friction and Corrosion-Resistant Orthodontic Stainless Steel Archwires with Functional Carbon Films

open access: yesNanomaterials
To mitigate the adverse effects of immersion in fluoride-containing solutions on the surface corrosion of orthodontic stainless steel archwires, carbon films were fabricated on these archwires under various deposition times and substrate bias voltages ...
Pengfei Wang, Minghui Hao, Shiqi Cheng
doaj   +1 more source

Comparison the effectiveness of pyruvic acid 50% and salicylic acid 30% in the treatment of acne

open access: yesJournal of Research in Medical Sciences, 2016
Background: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous follicles and one of the most common skin diseases. The peeling method has been recently found to be effective for acne treatment.
Fariba Jaffary   +3 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

The Impact of Peeling on Highland Barley’s Digestive Properties: In Vitro and In Vivo Insights

open access: yesFoods
Highland barley is a low-glycemic-index grain, and its slow-digesting starch can help delay or prevent the onset and progression of type Ⅱ diabetes.
Yuting Yan   +4 more
doaj   +1 more source

Croton oil peels [PDF]

open access: yesAesthetic Surgery Journal, 2008
This author discusses the utility and versatility of the modern croton oil peel, which, unlike older formulations, may be used for all ages and skin types for effective and long-lasting skin resurfacing. He provides the rationale for various croton oil concentrations, focusing on avoiding complications while achieving a desirable clinical result and ...
openaire   +3 more sources

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

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