Results 111 to 120 of about 1,857,257 (288)

Social Simulation That 'Peers into Peer Review' [PDF]

open access: yes
This article suggests to view peer review as a social interaction problem and shows reasons for social simulators to investigate it. Although essential for science, peer review is largely understudied and current attempts to reform it are not supported ...
Flaminio Squazzoni, K�roly Tak�cs
core  

Temporal expression normalisation in natural language texts [PDF]

open access: yes, 2012
Automatic annotation of temporal expressions is a research challenge of great interest in the field of information extraction. In this report, I describe a novel rule-based architecture, built on top of a pre-existing system, which is able to normalise ...
Filannino, Michele
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Peer-reviewer acknowledgments [PDF]

open access: yesJournal of Chiropractic Education, 2017
Acknowledgments to the peer reviewers for the journal and those who have participated in contributing scholarly works pertaining to chiropractic education are presented in this editorial.
openaire   +2 more sources

Is Peer Review in Decline? [PDF]

open access: yes
Over the past decade there has been a decline in the fraction of papers in top economics journals written by economists from the highest-ranked economics departments.
Glenn Ellison
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Commentary: High Intensity Physical Rehabilitation Later Than 24 h Post Stroke Is Beneficial in Patients: A Pilot Randomized Controlled Trial (RCT) Study in Mild to Moderate Ischemic Stroke

open access: yesFrontiers in Neurology, 2020
Mari Nakao   +11 more
doaj   +1 more source

Home - About - Disclaimer - Privacy