Results 91 to 100 of about 294,033 (277)

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Widespread Adoption of Information Technology in Primary Care Physician Offices in Denmark: A Case Study [PDF]

open access: yes, 2010
Describes the use of electronic medical records, standardized clinical communications, and patient identification numbers by Denmark's primary care physicians; a nonprofit organization's role in implementation and certification; and elements of ...
Denis Protti, Ib Johansen
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

“It’s more than a ride” veteran perceptions of peer specialist qualities and activities that were most valuable for post-incarceration reentry: a qualitative analysis

open access: yesHealth & Justice
Background Reentry veterans experience many barriers to achieving physical and psychological well-being. While peer specialists can provide important support to veterans as they readjust to life post-incarceration, their specific activities and qualities
Eric Richardson   +5 more
doaj   +1 more source

Evidence-based decision support for pediatric rheumatology reduces diagnostic errors. [PDF]

open access: yes, 2016
BACKGROUND: The number of trained specialists world-wide is insufficient to serve all children with pediatric rheumatologic disorders, even in the countries with robust medical resources. We evaluated the potential of diagnostic decision support software
Balu Athreya   +31 more
core   +2 more sources

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Ford Foundation Vietnam [PDF]

open access: yes, 2008
Provides an overview of the foundation's programs and key strategies in Vietnam in development finance; education and scholarship; environment and development; international cooperation; media, arts and culture; and sexuality and reproductive ...

core  

Profound vision loss impairs psychological well-being in young and middle-aged individuals. [PDF]

open access: yes, 2017
PurposeThe aim of this study was to evaluate the effects of profound vision loss on psychological well-being in adolescents, young adults, and middle-aged adults with regard to mood, interpersonal interactions, and career-related goals.
Baron, David   +8 more
core   +2 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

The Specialist in Today's University of Wisconsin--Extension [PDF]

open access: yes
As part of a comprehensive strategic planning effort undertaken by the University of Wisconsin-Extension, Cooperative Extension Service (UWEX-CES), a web-based survey of state specialists was undertaken in the fall of 2007. This manuscript represents the
Deller, Steven, Preissing, John
core  

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