Results 71 to 80 of about 294,033 (277)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Characterization of peer support services for substance use disorders in 11 US emergency departments in 2020: findings from a NIDA clinical trials network site selection process

Addiction Science & Clinical Practice
Introduction Emergency departments (ED) are incorporating Peer Support Specialists (PSSs) to help with patient care for substance use disorders (SUDs).
Lindsey K Jennings, Laura Lander, Tricia Lawdahl, Erin A. McClure, Angela Moreland, Jenna L. McCauley, Louise Haynes, Timothy Matheson, Richard Jones, Thomas E. Robey, Sarah Kawasaki, Phillip Moschella, Amer Raheemullah, Suzette Miller, Gina Gregovich, Deborah Waltman, Kathleen T. Brady, Kelly S. Barth   +17 more
doaj   +1 more source

Gateway to College: Lessons from Implementing a Rigorous Academic Program for At-Risk Young People [PDF]

, 2015
Despite efforts to improve the high school graduation rate in the United States, an estimated 7,200 students drop out of high school every day -- a staggering 1.3 million every year.
Brian Bayes, Jacklyn Altuna Willard, John Martinez   +2 more
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Systematizing peer recovery support services for substance use disorder: a taxonomy for measuring recovery milestones

Frontiers in Public Health
BackgroundRecovery from substance use disorder (SUD) is a complex and individualized process requiring multifaceted support systems. Peer recovery support services (PRSS), provided by Peer Workers, bridge the gap between formal intervention and personal ...
Kimberly Horn, Ryan E. Flinn, Angela Marie Hagaman, Kristyn Zajac, Lauren A. Hoffman, Melissa N. Poulsen, Camille C. Cioffi, Ducel Jean-Berluche, Ethan Spana, Patrick F. Hibbard, Tess K. Drazdowski, Aaron Hogue   +11 more
doaj   +1 more source

Genesys HealthWorks: Pursuing the Triple Aim Through a Primary Care-Based Delivery System, Integrated Self-Management Support, and Community Partnerships [PDF]

, 2010
Details Triple Aim pilot programs to engage primary care doctors in care coordination, prevention, and efficient use of specialty care through a physician-hospital organization; promote healthy behaviors; and extend access for the poor and ...
Douglas McCarthy, Sarah Klein
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Specialists’ learning from facilitating group peer telementoring: a qualitative study

BMC Medical Education
Background Group peer telementoring supports interprofessional learning through multi-directional and synchronous engagement where experienced and knowledgeable individuals exchange guidance and support with differently experienced and knowledgeable ...
R. Sam Larson, James W. Dearing, Nagesh Rao, Caryn E. Medved   +3 more
doaj   +1 more source

Examining the Feasibility, Acceptability, and Effectiveness of Remote Training on Community-Based Participatory Research: Single-Arm Pre-Post Pilot Study

Journal of Participatory Medicine
BackgroundOver the past decade, a growing body of scientific evidence has demonstrated that community engagement in research leads to more relevant research, enhances the uptake of research findings, and improves clinical outcomes.
Karen Fortuna, Andrew Bohm, Stephanie Lebby, Kisha Holden, Branka Agic, Theodore D Cosco, Robert Walker   +6 more
doaj   +1 more source

Developing a national item bank [PDF]

, 2004
The COLA project has been developing a large bank of assessment items for units across the Scottish further education curriculum since May 2003. These will be made available to learners mainly via colleges’ virtual learning environments. Many people have
MacDonald, Mary, Sclater, Niall
core   +1 more source