Results 71 to 80 of about 89,660 (267)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Extending the peer support specialist pathway for supporting recovery

Journal of Community Safety and Well-Being
Recovery Corps is a pioneering social innovation in behavioural health, addressing the critical need for peer-driven recovery support services amidst the ongoing substance use crisis in the United States. Leveraging AmeriCorps infrastructure, Recovery Corps recruits and trains individuals with substance use disorder (SUD) lived experience to provide ...
Anthony Coetzer-Liversage, Pete Nelson, Ben Suker   +2 more
openaire   +2 more sources

Compassionate Towards Ourselves: A Tool for Personal Recovery and Therapeutic Work of Peer Specialists

, 2022
Objective. Self-compassion is part of recovery for many people who experience mental illness. Peer specialists are mental health professionals who have experienced mental illness and use their recovery experiences to facilitate the healing of others ...
OFRA WALTER, BATEL HAZAN-LIRAN
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

The Integration of Peer Support Specialists: A Qualitative Study

, 2015
The integration of Peer Support Specialists (PSS’s) into the mental health workplace presents both a challenge and an opportunity. For this qualitative study seven Peer Support Specialists were interviewed regarding their experiences in the workplace ...
Smedberg, Maja B.
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Clarifying the role of the mental health peer specialist in Massachusetts, USA: insights from peer specialists, supervisors and clients

, 2013
Mental health peer specialists develop peer-to-peer relationships of trust with clients to improve their health and well-being, functioning in ways similar to community health workers.
Muhr, Kathy, Sefton, Laura A., Cabral, Linda M., Strother, Heather, Savageau, Judith A.   +4 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

A Recovery-Oriented Suicide Prevention Program Led by Peer Specialists for Veterans With Serious Mental Illness: Protocol for a Pilot Randomized Controlled Trial

JMIR Research Protocols
BackgroundVeterans with serious mental illness (SMI) have significantly elevated suicide risk compared to those without SMI. This group may also experience cognitive and functional impairments that complicate suicide prevention ...
Samantha Chalker, Jillian Carter, Yuki Imai, Colin Depp, Matthew Chinman   +4 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

2022 Spring The Beacon: TRIO Disability Support Services newsletter

, 2022
Director's Message -- Valentine's Day Community Service -- Tri-Alpha at WSU -- Spring 2022 Tutor program: Tutor Requests, Mark your calendar, Become a DSS tutor -- Welcome our new lead tutor: Magdalena Mollo Vinoly -- DSS Writing and Math specialists ...
TRIO Disability Support Services
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