Results 91 to 100 of about 1,496,607 (316)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
TrusNet: Peer-to-Peer Cryptographic Authentication [PDF]
, 2016 Originally, the Internet was meant as a general purpose communication protocol, transferring primarily text documents between interested parties. Over time, documents expanded to include pictures, videos and even web pages.
Bedard, Adrian, Bedard, Jonathan
core +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Competition against peer-to-peer networks [PDF]
In this paper, we consider the competition of providers of information products against P2P networks that offer illegal versions of the information products. Depending on the generic cost factor of downloading—incorporating factors including, among other
Herings, P. Jean-Jacques +2 more
core +1 more source
A Peer-to-Peer Architecture for Distributed Knowledge Management. [PDF]
, 2002 Most of the knowledge management systems of complex organizations are based on technological architectures that are in contradiction with the social processes of knowledge creation. In particular, centralized architectures are adopted to manage a process
Bonifacio, Matteo +3 more
core +2 more sources
Peer-to-Peer Multi-class Boosting [PDF]
, 2012 We focus on the problem of data mining over large-scale fully distributed databases, where each node stores only one data record. We assume that a data record is never allowed to leave the node it is stored at. Possible motivations for this assumption include privacy or a lack of a centralized infrastructure. To tackle this problem, earlier we proposed
Hegedűs István +4 more
openaire +3 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Graph Coloring using Peer-to-Peer Networks [PDF]
Computer Science Journal of Moldova, 2006 The popularity of distributed file systems continues to grow in last years. The reasons they are preferred over traditional centralized systems include fault tolerance, availability, scalability and performance.
Adrian Iftene, Cornelius Croitoru
doaj
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Islamic Economics Journal, 2018 Along with the development of technology, financial intermediary institutions in Indonesia also grew with the presence of technology-based financial services provider companies such as peer to peer lending company.
Satria Utama, Inayatul Ilahiyah
doaj +1 more source