Results 81 to 90 of about 99,123,269 (294)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
P2P-role: uma arquitetura de controle de acesso baseada em papéis para sistemas colaborativos peer-to-peer [PDF]
, 2005 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Ciência da Computação.Os sistemas Peer-to-Peer apresentam uma forma de computação distribuída onde cada participante atua como cliente e ...
Righi, Rafael da Rosa
core
PEER D5.3 USAGE STUDY Randomised controlled trial results
, 2012 This report reviews the findings of an experiment to measure the effect of exposing early article versions in repositories on downloads of the version of record at various publishers' web sites. The research design used was a randomised controlled trial (
Rowlands, Ian +2 more
core +1 more source
Frontiers in Energy ResearchAdapting to horizontal market structures faces several drivers and challenges in the context of sustainable energy transition. The inherently decentralized nature qualifies blockchain technology as the major technical driver in the transition to peer-to ...
Maya P, P. Abdul Salam
doaj +1 more source
Rise and Fall of the Peer-to-Peer Empire
Tsinghua Science and Technology, 2012 The essence of the peer-to-peer design philosophy is to design protocols for end hosts, or "peers", to work in collaboration to achieve a certain design objective, such as the sharing of a large file.
Baochun Li, Yuan Feng, Bo Li
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Internet Policy Review, 2016 This paper discusses self-labelling standards as sharing mediators in pirated versions of movies available online. Piracy has existed since the beginning of the film industry, challenging established rules and regulations.
Roberto Tietzmann, Liana Gross Furini
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Performance of locality-aware topologies for peer-to-peer live streaming [PDF]
, 2009 This study is concerned with the effect of overlay network topology on the performance of live streaming peer-to-peer systems. The study focuses on the evaluation of topologies which are aware of the delays experienced between different peers on the ...
Landa, R +4 more
core