Results 51 to 60 of about 63,196,727 (310)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Detection of P2P Botnets Based on Support Vector Machine: Case Study [PDF]
Engineering and Technology Journal, 2014 Botnet is a general term referring to a group of automated software robots that run without human intervention (malware code). Nowadays, Botnets produces a major threat to the cyber security (Information Assurance) of computing assets.
Nemir Ahmed Al-Azzawi +1 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Attrition Defenses for a Peer-to-Peer Digital Preservation System
, 2004 In peer-to-peer systems, attrition attacks include both traditional, network-level denial of service attacks as well as application-level attacks in which malign peers conspire to waste loyal peers' resources.
David S. H. Rosenthal +10 more
core +1 more source
, 2012 PEER (Publishing and the Ecology of European Research), supported by the EC eContentplus programme, has been investigating the potential effects of the large-scale, systematic depositing of authors' final peer-reviewed manuscripts (so called Green Open ...
Wallace, Julia
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Efficient and Effective Use of Peer Teaching for Medical Student Simulation
Western Journal of Emergency Medicine, 2017 Simulation is increasingly used in medical education, promoting active learning and retention; however, increasing use also requires considerable instructor resources.
House, Joseph +5 more
doaj +1 more source
Collusion in peer-to-peer systems [PDF]
Computer Networks, 2011 P2P systems are used to provide distributed storage, file sharing, video streaming, distributed gaming, and other applications based on the collaboration of participating peers and on the observation that sharing resources used sporadically leads to huge savings.
Ciccarelli, Gianluca +1 more
openaire +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Peer-Assisted Information-Centric Network (PICN): A Backward Compatible Solution
IEEE Access, 2017 Information-centric networking (ICN) is a promising solution for most of Internet applications where the content represents the core of the application.
Zeinab Zali +4 more
doaj +1 more source