Results 111 to 120 of about 179,604 (239)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

More Than Memories? Schema Transference from Media Characters to Real People [PDF]

, 2011
This study focused on whether personality traits and evaluations of television personalities are used to make inferences about new Social interaction partners. It tested the hypothesis that priming schemas of television personalities will bias inferences
Ray, Hilary
core   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

“It felt like a weight was being taken off of my shoulders”: findings from an intervention to support migrant adolescents and young people in KwaZulu-Natal, South Africa

SSM - Mental Health
In South Africa, many young people relocate from rural to urban areas for education, attending day schools while residing in rented accommodation. Migration exposes them to risk, including alcohol and drug abuse, sexual exploitation and violence.
Nondumiso Dlamini, Siphesihle Hlongwane, Carina Herbst, Maryam Shahmanesh, Nothando Ngwenya, Sarah Bernays, Janet Seeley   +6 more
doaj   +1 more source

Impacts of Covid-19 on peer-to-peer accommodation platforms: Host perceptions and responses. [PDF]

Int J Hosp Manag, 2020
Farmaki A, Miguel C, Drotarova MH, Aleksić A, Časni AČ, Efthymiadou F.   +5 more
europepmc   +1 more source

On Repairing Reasoning Reversals via Representational Refinements [PDF]

, 2006
Representation is a fluent. A mismatch between the real world and an agent’s representation of it can be signalled by unexpected failures (or successes) of the agent’s reasoning. The ‘real world ’ may include the ontologies of other agents.
Bundy, Alan, McNeill, Fiona, Walton, Christopher   +2 more
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Culture as a catalyst for regenerative co-creation: the role of yuanfen in driving customer voice through social bonds in P2P accommodation

Frontiers in Psychology
IntroductionAs tourism shifts from sustainability toward regeneration, active customer participation has become essential for revitalizing the peer-to-peer (P2P) accommodation sector.
Huifang Liu, Huifang Liu, Xiaoting Huang
doaj   +1 more source

Power dynamics in peer-to-peer accommodation: Insights from Airbnb hosts. [PDF]

Int J Hosp Manag, 2020
Farmaki A, Kaniadakis A.
europepmc   +1 more source